There is an urgent need for the development of a high-energy, micronutrient-dense food, such as a spread, for clinical and emergency nutrition. The spread to be used in the International Research on Infant Supplementation (IRIS) III trial will contain carotene-rich palm oil as a source of vitamin A and energy, and heme iron from slaughterhouse blood as an iron source. All other micronutrients shall come from a pre-mix. The product shall be designed for young children, in particular, but can be consumed by adults, as well. An efficacy study will be conducted for six months in children 6 to 12 months old.
BriendA., LacsalaR., PrudhonC., MounierB., GrelletyY., GoldenM.H.Ready-to-use therapeutic food for treatment of marasmus (letter). Lancet1999; 353: 1767–8.
2.
ScrimshawN.S.Nutritional potential of red palm oil for combating vitamin A deficiency. Food Nutr Bull2000; 21: 195–201.
3.
NagendranB., UnnithanU.R., ChooY.M., SundramK.Characteristics of red palm oil, a carotene- and vitamin E–rich refined oil for food uses. Food Nutr Bull2000; 21: 189–94.
4.
SolomonsN.W., JacobR.A.Studies on the bioavailability of zinc in humans: effects of heme and nonheme iron on the absorption of zinc. Am J Clin Nutr1981; 34: 475–82.
5.
MäurerA., SchümannK.Abattoir blood used in foods: an example of nutrition-environment interaction. SCN News2000; 21: 32–3.
6.
LopioreC., BrancaF.Strategies to fight anemia and growth retardation in Saharawi refugee children.Rome, ECHO, CISP, INRAN, 2001.
7.
GrossR.Micronutrient supplementation throughout the life cycle.New York: UNICEF, 2001.
8.
SmutsC.M., BenadéA.J., BergerJ., HopL.T., López de RomañaG., UntoroJ., KaryadiE., ErhardtJ., GrossR.IRIS I: A foodlet-based multiple-micronutrient intervention in 6- to 12-month-old infants at high risk of micronutrient malnutrition in four contrasting populations: description of a multicenter trial. Food Nutr Bull2003; 24: S27–S33.