Background: Amyloidosis affecting peripheral nerve is usually seen in primary amyloidosis. Methods: We are reporting on the case of a 74-year-old man with a 16-month history of progressive left radial nerve paralysis. Perioperative imaging detected an enlarged radial nerve in the middle-distal part of the arm. The patient had an antecedent of amyloid deposits in the lung. Results: A radial nerve amyloidosis was suspected and confirmed with a biopsy assisted by ultrasonography, resulting in a secondary amyloidosis form. Conclusions: Isolated radial nerve palsy due to nerve damage by amyloidosis has been reported before, but not in AA or secondary amyloidosis.
ChengRREskandariRWelshCTVarmaAK.A case of isolated amyloid light-chain amyloidosis of the radial nerve. J Neurosurg. 2016;15:1-5.
4.
DyckPJLambertEH.Dissociated sensation in amyloidosis: compound action potentials; quantitative histologic and teased fibers; and electron microscopic studies of sural nerve biopsies. Trans Am Neurol Assoc. 1968;93:112-115.
5.
González-LópezEGallego-DelgadoMGuzzo-MerelloG. Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction. Eur Heart J. 2015;36:2585-2594.
6.
HemminkiKLiXFörstiASundquistJSundquistK.Incidence and survival in non-hereditary amyloidosis in Sweden. BMC Public Health. 2012;12:974.
7.
KantaMEhlerEKoboutA. Rare case of a localized radial nerve amyloid neuropathy. J Clin Neuromuscul Dis. 2014;16(1):20-23.
8.
KyleRALinosABeardCM. Incidence and natural history of primary systemic amyloidosis in Olmsted County, Minnesota, 1950 through 1989. Blood. 1992;79(7):1817-1822.
9.
LachmannHJGoodmanHJGilberstsonJA. Natural history and outcome in systemic AA amyloidosis. N Engl J Med. 2007;356(23):2361-2371.
10.
NienhuisHLABijzetJHazenbergBPC. The prevalence and management of systemic amyloidosis in Western Countries. Kidney Dis (Basel). 2016;2:10-19.
11.
NordborgCKristensonKOlssonY. Involvement of the autonomous nervous system in primary and secondary amyloidosis. Acta Neurol Scand. 1973;49:31-38.
12.
PepysMB.Amyloidosis. Annu Rev Med. 2006;57:223-241.
13.
PerfettoFMoggi-PignoneALiviRTempestiniABergesioFMatucci-CerinicM.Systemic amyloidosis: a challenge for the rheumatologist. Nat Rev Rheumatol. 2010;6:417-429.
14.
PinneyJHSmithCJTaubeJB. Systemic amyloidosis in England: an epidemiological study. Br J Haematol. 2013;161(4):525-532.
15.
Real de AsúaDCostaRGalvánJMFilighedduMTTrujilloDCadiñanosJ.Systemic AA amyloidosis: epidemiology, diagnosis and management. Clin Epidemiol. 2014;6:369-377.
16.
SanchorawalaV.Light-chain (AL) amyloidosis: diagnosis and treatment. Clin J Am Soc Nephrol. 2006;1:1331-1341.
17.
SeilerSGIIIDesaiMJPayneSH.Tendon transfers for radial, median, and ulnar nerve palsy. J Am Acad Orthop Surg. 2013;21(1):675-684.
TanskanenMPeuralinnaTPolvikoskiT. Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: a population-based autopsy study. Ann Med. 2008;40:232-239.
20.
ThawaitSKChaudhryVThawaitGK. High-resolution MR neurography of diffuse peripheral nerve lesions. AJNR Am J Neuroradiol. 2011;32:1365-1372.
21.
VucicSChongPSCrosD.Atypical presentations of primary amyloid neuropathy. Muscle Nerve. 2003;28:696-702.
