Introduction: The aim of this study was to review our short-term results to long-term results of wrist arthroplasty from 2 centers. Methods and Material: Remotion implant is a modular total wrist joint prosthesis. Uncemented technique used except for 2 cases. The prosthesis used for patients with rheumatoid arthritis in 95 cases, degenerative arthritis in 32, and posttraumatic arthritis in 23. Patients evaluated preoperatively and postoperatively with range of motion (ROM), grip strength, and visual analogue scale (VAS) scores of 0 to 100 mm of pain and satisfaction. Functional and general outcomes were evaluated using the Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) and Patient Rated Wrist Evaluation (PRWE) questionnaires. Radiographs were obtained preoperatively and at follow-up. The procedure performed in 159 patients, 47 men and 112 women. Their median age was 61 years (24-86). Diagnosis was rheumatoid arthritis in 95 cases, degenerative arthritis in 32, and posttraumatic arthritis in 23. Median follow-up was 50 months (range, 3-133). Results: Wrist extension and flexion was preoperatively 35/35° and at follow-up 35/30°. Radial/ulnar deviation was 10/25° versus 10/30° postoperatively. Grip strength, in KgF, was preoperatively 10 (range, 0-64) and at follow-up 16 (0-70). VAS pain was preoperatively at rest/activity 43/68, and at follow-up 5/21. QuickDASH and PRWE scores were preoperatively 59 and 66, respectively, and at follow-up 36 and 29. VAS satisfaction preoperatively was 14 mm (0-100) at latest follow-up 87 mm (4-100). No infections or dislocations encountered. Ten prosthesis revised. Arthrodesis in 4 cases and in 6 cases, some of the components revised to new components. Conclusions: The short-term to long-term outcome indicates that total wrist arthroplasty is a viable option with unchanged ROM and improvement of pain, grip strength, QuickDASH, PRWE, and satisfaction. We consider our complication rate more than acceptable.