Objective: To report a series of cases of congenital flexion deformity of the long, ring, and little fingers with an aberrant origin of the flexor digitorum profundus and to compare this disease with the Volkmann’s contracture. Materials and Methods: Five cases of congenital flexion deformity of the long, ring, and little fingers with an aberrant origin of the flexor digitorum profundus were reported. Two of them were children. All the patients were misdiagnosed as the Volkmann’s contracture in the local clinics. Radiographs and 3-D computed tomography (3-D CT) of the involved forearm were performed. There were no neural disorders in any case. Results: The 3-D CT showed there was a bone prominence on the proximal part of the ulna. During the operation, we could find an aberrant origin of the flexor digitorum profundus of 3 to 5 fingers was attached to the bone prominence. Resection of the aberrant origin could achieve a thorough release in children cases but further muscle sliding procedure was needed in adult cases. Conclusion: Congenital flexion deformity of the long, ring, and little fingers with an aberrant origin of the flexor digitorum profundus is a potentially ignored disease. Finding the bone prominence on the proximal part of the ulna is helpful for the early diagnosis. Resection of the aberrant origin with muscle sliding procedure can get good result.