Effects of Electrospinning Setup and Process Parameters on Nanofiber Morphology Intended for the Modification of Quartz Crystal Microbalance Surfaces

Abstract

To improve the performance of mass sensitive biosensors, the surface of a piezoelectric quartz crystal transducer, is expanded by employing electrospun nanofibers to its surface. This work describes the effect of vertical - horizontal electrospinning setups and electrospinning parameters on fiber morphology. The research objective was to obtain finer and non-beaded fiber morphologies, via controllable and repeatable process parameters, for further applications of QCM surfaces in high performance DNA-, Aptamer-, Immunosensor applications.