The Middle East Research Ethics Training Initiative (MERETI), established in 2004 with funding from the Fogarty International Center at the NIH, aimed to enhance research ethics capacity in the Middle East North Africa (MENA) region. Initially focused on Egypt, MERETI expanded to other Arab countries, providing advanced training in international research ethics to over 100 individuals. The program emphasized additional skills in research methodology, pedagogy, scientific writing, and leadership. MERETI's training evolved from a one-year program to a two-year model incorporating sequential hybrid/blended and asynchronous online components and, eventually, included a fully online 12-credit graduate certificate in research ethics. The program's impact is demonstrated through the professional achievements of its trainees, which included publishing in peer-reviewed journals, assuming key roles in national research ethics committees and ministries of health and contributing to the development of ethics research practices in their respective countries. MERETI also fostered a sustainable Egyptian network of research ethics committees.
AbdelkreemE.IbrahimM.ElateekS.SilvermanH. (2024). Perceptions of the research integrity climate in Egyptian universities: A survey among academic researchers. Journal of Empirical Research. on Human Research Ethics, 19(4–5), 175–185. https://doi.org/10.1177/15562646241273097
2.
AbdelnabyA.AbbasN.AbdelhafizA. S.MohammedZ.YasserS.TahaN.SilvermanH. J. (2024). knowledge, attitudes, and self-reported practices regarding plagiarism among health researchers in Egypt and Lebanon: a multicenter questionnaire study. Research ethics. https://doi.org/10.1177/17470161241291937
3.
AdarmouchL. (2017). Biomedical research law in Morocco. In SilvermanH. (Ed.), Research Ethics in the Arab Region. Cham: Springer International Publishing.
4.
Al-OmariA.HussainiM. (2017). Research ethics governance in the Arab region: Jordan. In H. Silverman (Ed.), Research Ethics in the Arab Region. Springer International.
5.
Al-SoleitiM.Abu AdiM.NashwanA.Rafla-YuanE. (2021). Barriers and opportunities for refugee mental health services: Clinician recommendations from Jordan. Global Mental Health (Camb), 8, e38. https://doi.org/10.1017/gmh.2021.36
6.
Amany ElaminA.IbrahimM.AbuidrisD.MohamedK.MohammedS. (2015). Part I: Cancer in Sudan-burden distribution, and trends breast, gynecological, and prostate cancers. Cancer Medicine. https://doi.org/10.1002/cam4.378
7.
AtallahD.MoubarakM.El KassisN. (2018). Clinical research ethics review process in Lebanon: Efficiency and functions of research ethics committees - results from a descriptive questionnaire-based study. Trials, 19(1), 27. https://doi.org/10.1186/s13063-017-2397-2
8.
BadawiM. M.SalaheldinM. A.IdrisA. B.IdrisE. B.MohamedS. G. (2024). Tuberculosis in Sudan: Systematic review and meta analysis. BMC Pulmonary Medicine, 24(1), 51. https://doi.org/10.1186/s12890-024-02865-6
CharaniE.CunningtonA. J.YousifA. H. A.Seed AhmedM.AhmedA. E. M.BabikerS.Taylor-RobinsonS. D. (2019). In transition: Current health challenges and priorities in Sudan. BMJ Glob Health, 4(4), e001723. https://doi.org/10.1136/bmjgh-2019-001723
11.
Egyptian Network of Research Ethics Committees (ENREC). (2024). Accreditation of Research Ethics Committees. Available at:https://www.enrec.org/assessment
12.
ElgamriA.MohammedZ.El-RhaziK.ShahrouriM.AhramM.Al-AbbasA. M.SilvermanH. (2023). Challenges Facing Arab Researchers in Publishing Scientific Research: A Qualitative Interview Study. Research Square. https://doi.org/10.21203/rs.3.rs-3129329/v1
13.
ElgharablyA.GomaaA. I.CrosseyM. M.NorsworthyP. J.WakedI.Taylor-RobinsonS. D. (2017). Hepatitis C in Egypt - past, present, and future. International Journal of General Medicine, 10, 1–6. https://doi.org/10.2147/IJGM.S119301
14.
ElmorshedyH.BergquistR.FayedA.GuirguisW.Abdel-GawwadA.SafaaE.BarakatR. (2020). Elimination of schistosomiasis requires multifactorial diagnostics: Evidence from high- and low-prevalence areas in the Nile Delta Egypt. Infectious Disease of Poverty, 9, 31.
15.
El RhaziK.BennaniB.El FakirS.BolyA.BekkaliR.ZidouhA.NejjariC. (2014). Public awareness of cancer risk factors in the Moroccan population: A population-based cross-sectional study. BMC Cancer, 14, 695. https://doi.org/10.1186/1471-2407-14-695
16.
EnnassiriW.JaouhariS.SabouniR.CherkiW.CharofR.Filali-MaltoufA.LahlouO. (2018). Analysis of isoniazid and rifampicin resistance in Mycobacterium tuberculosis isolates in Morocco using GenoType((R)) MTBDRplus assay. Journal of Global Antimicrobial Resistance, 12, 197–201. https://doi.org/10.1016/j.jgar.2017.09.017
FakhouriS. (2016). Healthcare in Egypt: A synopsis on the system and the anticipated reforms. World Hospitals and Health Services, 52(3), 21–23. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/30707809
19.
FelaefelM.SalemM.JaafarR.JassimG.EdwardsH.Rashid-DoubellF.SilvermanH. (2018). A cross-sectional survey study to assess prevalence and attitudes regarding research misconduct among investigators in the Middle East. J Acad Ethics, 16(1), 71–87. https://doi.org/10.1007/s10805-017-9295-9
Fogarty International Center (FIC). (2024b). Notice of Special Interest (NOSI) for Administrative Supplements to Fogarty International Center's Research Training and Educational Development Grants: Opportunity Pathways in Global Health Research and Training. Available at:https://grants.nih.gov/grants/guide/notice-files/NOT-TW-24-006.html [Press release]
HirschB. R.LockeS. C.AbernethyA. P. (2016). Experience of the national cancer institute community cancer centers program on community-based cancer clinical trials activity. Journal of Oncology Practice, 12(4), e350–358. https://doi.org/10.1200/JOP.2015.005090
IbrahimM. E.AdarmouchL.ElgamriA.Abd ElHafeezS.MohammedZ.AbdelgawadF.SilvermanH. (2024). Researchers’ perspectives regarding ethical issues of biobank research in the arab region. Biopreservation and Biobanking, 22(2), 98–109. https://doi.org/10.1089/bio.2022.0112
27.
KassN. E.AliJ.HallezK.HyderA. A. (2016). Bioethics training programmes for Africa: Evaluating professional and bioethics-related achievements of African trainees after a decade of fogarty NIH investment. BMJ Open, 6(9), e012758. https://doi.org/10.1136/bmjopen-2016-012758
28.
KerbageH.MarranconiF.ChamounY.BrunetA.RichaS.ZamanS. (2020). Mental health services for Syrian refugees in Lebanon: perceptions and experiences of professionals and refugees. Qualitative Health Research, 30(6), 849–864. https://doi.org/10.1177/1049732319895241
29.
KouyoumjianS. P.MumtazG. R.HilmiN.ZidouhA.El RhilaniH.AlamiK.BennaniA.GouwsE.GhysP. D.Abu-RaddadL. J. (2013). The epidemiology of HIV infection in Morocco: Systematic review and data synthesis. International Journal of STD & AIDS, 24(7), 507–516. https://doi.org/10.1177/0956462413477971
30.
Lebanon Law No. 81/2018 Relating to Electronic Transactions and Personal Data (2018) Available at: https://www.lexismiddleeast.com/law/Lebanon/Law_81_2018.
MansourH.ZakiN.AbdelhaiR.SabryN.SilvermanH.El-KamaryS. S. (2015). Investigating the informed consent process, therapeutic misconception and motivations of Egyptian research participants: A qualitative pilot study. Eastern Mediterranean Health Journal, 21(3), 155–163. https://doi.org/10.26719/2015.21.3.155
33.
MartinsonB. C.ThrushC. R.Lauren CrainA. (2013). Development and validation of the Survey of Organizational Research Climate (SORC). Science and Engineering Ethics, 19(3), 813–834. https://doi.org/10.1007/s11948-012-9410-7
34.
MarzoukD.Abd El AalW.SalehA.SleemH.KhyattiM.MaziniL.AnwarW. A. (2014). Overview on health research ethics in Egypt and North Africa. European Journal of Public Health, 24(Suppl 1), 87–91. https://doi.org/10.1093/eurpub/cku110
35.
MatarA.SilvermanH. J. (2022). Ethical analysis of Egypt's law regulating clinical research. Journal of Empirical Research. on Human Research Ethics, 17(4), 494–503. https://doi.org/10.1177/15562646221096188
36.
MohammedZ.AbdelgawadF.AhramM.IbrahimM. E.ElgamriA.GamelE.SilvermanH. (2024). Opinions and attitudes of research ethics committees in arab countries in the Middle East and North African region toward ethical issues involving biobank research. Research Ethics, 20(1), 1–8. https://doi.org/10.1177/17470161231185510
37.
Morocco - National Commission for the Protection of Personal Data Protection (CNDP) (2009) Available at: https://www.dgssi.gov.ma/sites/default/files/legislative/brochure/2024-07/law%2009-08%20in%20french.pdf
38.
Mumtaz, G. R., Kouyoumjian, S. P., Hilmi, N., Zidouh, A., El Rhilani, H., Alami, K., Bennani, A., Gouws, E., Ghys, P. D., Abu-Raddad, L. J. (2013). The distribution of new HIV infections by mode of exposure in Morocco. Sexually Transmitted Infections, 89(Suppl 3), iii49–56. https://doi.org/10.1136/sextrans-2012-050844
OmerS. A.IdressH. E.AdamI.AbdelrahimM.NoureldeinA. N.AbdelrazigA. M.ElhassanM. O.SulaimanS. M. (2017). Placental malaria and its effect on pregnancy outcomes in Sudanese women from Blue Nile State. Malaria Journal, 16, 374. https://doi.org/10.1186/s12936-017-2028-0
OrtonM.AgarwalS.MuhozaP.VasudevanL.VuA. (2018). Strengthening delivery of health services using digital devices. Global Health: Science and Practice, 6(Suppl 1), S61–S71. https://doi.org/10.9745/GHSP-D-18-00229
RihaniR.JehaS.NababtehM.Rodriguez-GalindoC.MansourA.SultanI. (2023). The burden and scope of childhood cancer in displaced patients in Jordan: The King Hussein Cancer Center and Foundation Experience. Frontiers in Oncology, 13, 1112788. https://doi.org/10.3389/fonc.2023.1112788
47.
SamiS.MayaiA.SheehyG.LightmanN.BoermaT.WildH.TappisH.OchanW.WanyamaJ.SpiegelP. (2020). Maternal and child health service delivery in conflict-affected settings: A case study example from Upper Nile and Unity states, South Sudan. Conflict and Health, 14, 34. https://doi.org/10.1186/s13031-020-00272-2
48.
SidahmedS.GeyerS.BellerJ. (2023). Socioeconomic inequalities in diabetes prevalence: The case of Egypt between 2008 and 2015. BMC Public Health, 23(1), 1669. https://doi.org/10.1186/s12889-023-16606-7
49.
SilvermanH. (2017). Research Ethics in the Arab Region. Springer International.
50.
SilvermanH.EdwardsH.ShamooA.MatarA. (2013). Enhancing research ethics capacity in the Middle East: Experience and challenges of a Fogarty-sponsored training program. Journal of Empirical Research. on Human Research Ethics, 8(5), 40–51. https://doi.org/10.1525/jer.2013.8.5.40
51.
SilvermanH.SleemH.MoodleyK.KumarN.NaidooS.SubramanianT.MoniM. (2015). Results of a self-assessment tool to assess the operational characteristics of research ethics committees in low- and middle-income countries. Journal of Medical Ethics, 41(4), 332–337. https://doi.org/10.1136/medethics-2013-101587
52.
SkalliS.HassikouR.ArahouM. (2019). An ethnobotanical survey of medicinal plants used for diabetes treatment in Rabat Morocco. Heliyon, 5(3), e01421. https://doi.org/10.1016/j.heliyon.2019.e01421
53.
SleemH. (2024). Egyptian Network of Research Ethics Committees. Available at:http://www.enrec.org
54.
SleemH.AdelhaiR.Al-AbdallatI.Al-NaifM.GabrH.KehilE. T.SilvermanH. (2010). Development of an accessible self-assessment tool for research ethics committees in developing countries. Journal of Empirical Research. on Human Research Ethics, 6, 85–96. https://doi.org/10.1525/jer.2010.5.3.85
55.
SleemH.SilvermanH. J. (2024). Revision of a self-assessment tool for research ethics committees in low- and middle-income countries: Incorporation of elements that safeguard participants’ rights and welfare. Developing World Bioethics. https://doi.org/10.1111/dewb.12469
56.
Tappis, H., Lyles, E., Burton, A., Jordan Health Access Study Team Arwa Oweis Laila-Akhu Zaheya Timothy Roberton Gilbert Burnham William Weiss, Lebanon Health Access Study Team Baptiste Hanquart Lara Chela Nour Aridi Nour Kassab Aline Keyrouz Deena Al-Shatti Francois de La Roche Michael Woodman, & Doocy, S. (2017). Maternal health care utilization among Syrian refugees in Lebanon and Jordan. Maternal and Child Health Journal, 21(9), 1798–1807. https://doi.org/10.1007/s10995-017-2315-y
