Sage Journals: Discover world-class research

Abstract

Obtaining effective informed consent from research participants is a prerequisite to the conduct of an ethically sound research. Yet it is believed that obtaining quality informed consent is generally difficult in settings with low socioeconomic status. This is so because of the alleged undue inducements and therapeutic misconception among participants. However, there is a dearth of data on factors that motivate research participants to take part in research. Hence, this study was aimed at filling this gap in the Malawian context. We conducted 18 focus group discussions with community members in urban and rural communities of Blantyre in Malawi. Most participants reported that they accepted the invitation to participate in research because of better quality treatment during study also known as ancillary care, monetary and material incentives given to participants, and thorough medical diagnosis.

Keywords

consent motivation biomedical research focus group discussions

Get full access to this article

View all access options for this article.

References

Bentley

J. P.

Thacker

P. G.

(2004). The influence of risk and monetary payment on the research participation decision making process. Journal of Medical Ethics, 30, 293-298. doi:10.1136/jme.2002.001594

Council for International Organizations of Medical Sciences. (2002). International ethical guidelines for biomedical research involving human subjects. Geneva, Switzerland. Retrieved from http://www.cioms.ch/publications/guidelines/guidelines_nov_2002_blurb.htm

Doshi

M. S.

Kulkarni

S. P.

Ghia

C. J.

Gogtay

N. J.

Thatte

U. M.

(2013). Evaluation of factors that motivate participants to consent for non-therapeutic trials in India. Journal of Medical Ethics, 39, 391-396. doi:10.1136/medethics-2012-100755

Emanuel

E. J.

Wendler

Killen

Grady

(2004). What makes clinical research in developing countries ethical? Journal of Infectious Diseases, 189, 930-937. doi:10.1086/381709

Grady

(2005). Payment of clinical research subjects. Journal of Clinical Investigation, 115, 1681-1687. doi:10.1172/JCI25694

Hawkins

Emanuel

(2008). Exploitation and developing countries: The ethics of clinical research. Princeton, NJ: Princeton University Press.

Lidz

C. W.

Appelbaum

P. S.

Grisso

Renaud

(2004). Therapeutic misconception and the appreciation of risks in clinical trials. Social Science & Medicine, 58, 1689-1697. doi:10.1016/S0277-9536(03)00338-1

Lynöe

Hyder

Chowdhury

Ekstrom

(2001). Obtaining informed consent in Bangladesh. The New England Journal of Medicine, 344, 460-461. doi:10.1056/NEJM200102083440617

Mfutso-Bengo

J. M.

Taylor

T. E.

(2001). Ethical aspects of clinical biomedical research in developing countries. Malawi Medical Journal, 13(2), 24-25.

10.

Molyneux

C. S.

Peshu

Marsh

(2004). Understanding informed consent in a low-income setting: Three case studies from the Kenyan coast. Social Science & Medicine, 59, 2547-2559.

11.

Nappo

S. A.

Iafrate

G. B.

Sanchez

Z. M.

(2013). Motives for participating in a clinical research: A pilot study in Brazil. Biomedical Central Public Health, 13, Article 19. doi:10.1186/1471-2458-13-19

12.

Pace

Grady

Emanuel

E. J.

(2003, August 28). What we don’t know about informed consent. Science and Development Network. Retrieved from http://www.scidev.net/global/health/opinion/what-we-dont-know-about-informed-consent.html

Motivational Factors for Participation in Biomedical Research

Abstract

Keywords

Get full access to this article

References