Restricted accessResearch articleFirst published online 2026-3
Characterization of Neurophysiological,Motor,and Emotional Biomarkers in Adolescents with ASD: An Integrated Analysis with qEEG,Facial Expression,and Biomechanics Analysis
This study investigated perceptual differences between adolescents with Autism Spectrum Disorder (ASD) and neurotypical individuals using a multidimensional approach involving quantitative electroencephalography (qEEG), biomechanical analysis with Movement Element Decomposition (MED), and facial microexpression tracking via FaceReader software. The study included 22 adolescents (8 with ASD and 14 controls), evaluated under four experimental conditions: rest (eyes open and closed) and exposure to visual/auditory stimuli. Findings indicated increased Delta band activity in the ASD group, absence of Alpha band reactivity, greater postural instability, altered oscillation patterns, and a predominance of neutral emotional expressions. The results suggest that individuals with ASD exhibit distinct patterns of sensory, motor, and emotional processing, highlighting the potential of these tools as biomarkers for diagnosis and intervention.
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