Structure of the Spontaneous All Night Sleep in Epileptics with Polysomnography

Abstract

Twenty epileptics and 11 healthy controls were investigated with polysomnography. Epileptics with interictal discharges had significantly longer total recording time and longer REM latency than the controls (P<0.05). Epileptics had a more fragmentized sleep than controls. Sleep efficiency of patients with interictal discharges was lower than that of patients without them (P<0.05). Among the patients with interictal discharges, those with partial seizures had a significantly higher arousal number than those with generalized seizures (P<0.05). The number of NREM stage shifts in patients with partial seizures tended to be higher than in those with generalized seizures.

Keywords

Key Words Electroencephalography Epilepsy Sleep Sleep Structure Sleep-waking Cycle

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References

Michaels

. Sleep and Epilepsy Sleep Medicine. Oxford University Press Inc.; 1999: 350–372.

Declerck

. Interaction Epilepsy, Sleep, Antiepileptics, Clinical Neurophysiological Study. Lisse

B. V.

, Netherlands: Swets & Zeitlinger; 1983: 3–6.

Melissa

Rodney

. Interaction between sleep and epilepsy. J Clin Neurophysiol 2001;18:106–127.

Tong

Cao

Lee

Fundamentals and Clinical Practice of Sleep Disordered Breathing. Beijing: People's Military Medical Publisher; 2001: 20–26.

Boselli

Parrino

Smerieri

Effect of age EEG arousals in normal sleep. Sleep 1998;21:351–357.

Jacques

Marie

Jean-Marc

S-H

Sleep and focal epilepsy: a study of patients implanted with depth electrodes. In: Wolf

Dam

Janz

(eds). Advances in Epileptology. New York: Raven Press 1987;166: 705–707.

Touchon

Baldy-Moulinier

Billiard

Sleep instabilities in temporal lobe epilepsy. In: Wolf

Dam

Janz

(eds). Advances in Epileptology. New York: Raven Press 1987;76: 709–711.

Giovanni

Liborio

Sivio

Effects of generalized interictal EEG discharges on sleep stability: assessment by means of cyclic alternating pattern. Epilepsia 1992;33:317–326.

Montplaisir

Laverdiere

Saint-Hilaire

J-M

Sleep and focal epilepsy: a study of patients implanted with depth electrodes. In: Wolf

Dam

Janz

(eds). Advances in Epileptology. New York: Raven Press 1987;16: 705–708.

10.

Shouse

Farber

Staba

. Physiological basis: how NREM sleep components can promote and REM sleep components can suppress seizure discharge propagation. Clin Neurophysiol 2000;111(suppl 1.2): S9–S18.

11.

Fabio

Anna

Grazia

Effect of antiepileptic drugs on sleep. Clin Neurophysiol 2000;111(suppl 1.2): S115–S119.