Making the Cut in Dental Enamel—The Discovery of Enamelysin (MMP-20)

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References

Bartlett JD, Simmer JP, Xue J, Margolis HC, Moreno EC -1996-. Molecular cloning and mRNA tissue distribution of a novel matrix metalloproteinase isolated from porcine enamel organ. Gene 183:123–128.

Bartlett JD, Beniash E, Lee DH, Smith CE -2004-. Decreased mineral content in MMP-20 null mouse enamel is prominent during the maturation stage. J Dent Res 83:909–913.

Bègue-Kirn C, Krebsbach PH, Bartlett JD, Butler WT -1998-. Dentin sialoprotein, dentin phosphoprotein, enamelysin and ameloblastin: tooth-specific molecules that are distinctively expressed during murine dental differentiation. Eur J Oral Sci 106:963–970.

Caterina JJ, Skobe Z, Shi J, Ding Y, Simmer JP, Birkedal-Hansen H, et al. -2002-. Enamelysin -matrix metalloproteinase 20--deficient mice display an amelogenesis imperfecta phenotype. J Biol Chem 277:49598–49604.

Fukae M, Tanabe T, Uchida T, Lee SK, Ryu OH, Murakami C, et al. -1998-. Enamelysin -matrix metalloproteinase-20-: localization in the developing tooth and effects of pH and calcium on amelogenin hydrolysis. J Dent Res 77:1580–1588.

Hu JC, Sun X, Zhang C, Liu S, Bartlett JD, Simmer JP -2002-. Enamelysin and kallikrein-4 mRNA expression in developing mouse molars. Eur J Oral Sci 110:307–315.

Kim JW, Simmer JP, Hart TC, Hart PS, Ramaswami MD, Bartlett JD, et al. -2005-. MMP-20 mutation in autosomal recessive pigmented hypomaturation amelogenesis imperfecta. J Med Genet 42:271–275.

Llano E, Pendas AM, Knauper V, Sorsa T, Salo T, Salido E, et al. -1997-. Identification and structural and functional characterization of human enamelysin -MMP-20-. Biochemistry 36:15101–15108.

Overall CM, Limeback H -1988-. Identification and characterization of enamel proteinases isolated from developing enamel. Amelogeninolytic serine proteinases are associated with enamel maturation in pig. Biochem J 256:965–972.

10.

Palosaari H, Ding Y, Larmas M, Sorsa T, Bartlett JD, Salo T, et al. -2002-. Regulation and interactions of MT1-MMP and MMP-20 in human odontoblasts and pulp tissue in vitro. J Dent Res 81:354–359.

11.

Ryu OH, Fincham AG, Hu CC, Zhang C, Qian Q, Bartlett JD, et al. -1999-. Characterization of recombinant pig enamelysin activity and cleavage of recombinant pig and mouse amelogenins. J Dent Res 78:743–750.

12.

Takata T, Zhao M, Uchida T, Wang T, Aoki T, Bartlett JD, et al. -2000-. Immunohistochemical detection and distribution of enamelysin -MMP-20- in human odontogenic tumors. J Dent Res 79:1608–1613.