The opportunities presented by subjects-condition (SxC) interactions are discussed after an introduction to their nature. Operator Strategy Differences (SDs), Scale-of-Measurement Effects (SOMs), and Condition Requirement Differences (CRDs) are each seen as potential sources of SxC interactions. It is shown that SxC interactions can (1) frequently be detected using an analysis of “error” variances approach, (2) be characterized in terms of their nature, and (3) enhance the utility of research results (once characterized). It is recommended that subjects-condition (SxC) interactions be routinely evaluated in human factors research.
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