This study was designed to determine if language, motor planning and memory could be identified as discrete components of performance. One hundred and thirty-three control subjects and 141 subjects diagnosed as having senile dementia of the Alzheimer type (SDAT) were studied The results suggest that the patterns of deficits in language, memory, and praxis are highly individualized Previous work has demonstrated the presence of apraxia in moderately and severely demented persons, and this study suggests that apraxia contributes significantly to dysfunction in some persons with SDAT. The results of this investigation support the need for multidimensional assessment and individualized care planning for persons with SDAT.
AlzheimerA. (1907). Uber eine eigenartige erkränkung der hirnrinde [On a peculiar disorder of the cerebral cortex]. WilkensR. H.BrodyI. E. (Trans.), Archives of Neurology, 21, 109–110. (Reprinted from Allgemeine Zeitschrift für Psychiatrische und Psychisch-Gerichtliche Medizin, 1907, 64, 146).
2.
BaumC.EdwardsD. (1987, April). Performance components in senile dementia of the Alzheimer's type. Paper presented at the American Occupational Therapy Association Annual Conference, Indianapolis, IN.
3.
BentonA. L.FogelM. L. (1962). Three-dimensional constructional praxis: A clinical test. Archives of Neurology, 7, 347–354.
4.
BergL. (1984). Clinical dementia rating. British Journal of Psychiatry, 140, 339.
5.
BergL.HughesC. P.CohenL. A.DanzigerW. L.MartinR. L.KnesevichJ. (1982). Mild dementia of Alzheimer type: Research diagnostic criteria, recruitment and description of a study population. Journal of Neurology, Neurosurgery and Psychiatry, 45, 962–968.
6.
BrodyE. M. (1985). Parent care as a normative family stress (Donald P. Kent Memorial Lecture). The Gerontologist, 25, 19–29.
7.
BrownJ. (1972). Aphasia, apraxia, and agnosia (pp. 157–160). Springfield, IL: Charles C Thomas.
8.
BurkeW. J.MillerJ. P.RubinE.MorrisJ. C.CobenL. A.DuchekJ.WittelsI. G.BergL. (1988). Reliability of the Washington University Clinical Dementia Rating (CDR). Archives of Neurology, 45, 31–32.
9.
DeRenziE.MottiF.NichelliP. (1980). Imitating gestures, a quantitative approach to ideomotor apraxia. Archives of Neurology, 37, 6.
10.
DeRenziE.PiecjuroA.VignoloL. A. (1968). Ideational apraxia, a quantitative study. Neuropsychology, 6, 41–52.
11.
DeuelR. K.FeeleyC.BonskowskiC. (1984). Manual apraxia in learning disabled children. Child Neurology Abstracts. Annals of Neurology, 16, 388.
12.
EdwardsD. F.BaumC. M.DeuelR.HegbergA. P. (1987). Apraxia in Alzheimer's disease: The development of a quantitative measure. Manuscript submitted for publication.
13.
ErnstB.DalbyM. A. (1970). Gnostic-praxic disturbance in presenile dementia. Acta Neurologica Scandinavica, 46(Suppl. 43), 101–102.
14.
FosterN. L.ChaseT.PatronasN.GillespieM.FedioP. (1986). Cerebral mapping of apraxia in Alzheimer's disease by positron emission tomography. Annals of Neurology, 19, 139–143.
15.
GeschwindN.DamasioA. (1985). Apraxia. In FrederikJ. (Ed.), Handbook of clinical neurology (Vol. 45, pp. 423–431). New York: Wiley.
16.
GoodglassH.KaplanE. (1972). The assessment of aphasia and related disorders. Philadelphia: Lea & Febiger.
17.
HughesC. P.BergL.DanzigerW.CobenL.MartinR. (1982). A new clinical scale for the staging of dementia. British Journal of Psychiatry, 140, 566–572.
18.
KerlingerF.PedzhaurE. (1973). Multiple regression in behavioral research. New York: Holt, Rinehart & Winston.
19.
MorrisJ. G.McKeelD. W.FullingK.TorachR.BergL. (in press). Validation of clinical diagnostic criteria for Alzheimer's disease. Annals of Neurology.
20.
MuramatoO.SugishitaM.AndoK. (1984). Cholinergic system and constructional praxis: A further study of physostigmine in Alzheimer's disease. Journal of Neurology, Neurosurgery and Psychiatry, 47, 485–491.
21.
SaxtonJ.HousleyS.BeckerJ. T.BoilerF. (1986, August). Cognitive function and activities of daily living in Alzheimer's disease. Paper presented at the meeting of the American Psychological Association, Washington, DC.
22.
SloanW. (1955). The Lincoln Osestsky Motor Development Scale. Geriatric Psychology Monograph, 51, 182–252.
23.
StillC. N.GoldschmidtT. J.MallinR. (1983). Mini Object Test: A new brief clinical assessment for aphasia-apraxia-agnosia. Southern Medical Journal, 76, 52–54.
24.
StorandtM.BotwinickJ.DanzigerW. L. (1984). Psychometric differentiation of mild senile dementia of the Alzheimer's type. Archives of Neurology, 41, 497–499.
