Management of Femoral Lymphatic Complications Following Synthetic Lower Extremity Revascularization: Early and Late Results

Abstract

Lymphatic complications following synthetic graft placement in the groin may be associated with prolonged drainage leading to the development of wound infection, which may involve the underlying prosthetic graft. To determine associated early and late mortality and morbidity and to develop guidelines for optimal management, the authors reviewed their department's recent experience with this problem.

From 1982 to 1996, 32 femoral lymphatic complications (29 lymphocutaneous fistulas and 3 lymphoceles) were treated in 26 patients (16 men and 10 women, mean age 68 years) who had undergone lower extremity revascularization utilizing synthetic graft material. Patients with clinical evidence of graft infection or those with lymphatic complications following autogenous reconstructions were excluded from analysis. Underlying grafts involved the aortofemoral segment in 63% (20/32), the femorofemoral segment in 16% (5/32), the femorodistal segment in 13% (4/32), and the axillofemoral segment in 9% (3/32). Presenting symptoms were wound drainage in 27 limbs (91%), a groin mass in 3 (9%), and both in 6% (2/32). Management consisted of surgical exploration and lymphatic ligation with or without sclerosis in 24 limbs (75%) and local measures only in 8 (25%). Mean late follow-up was 3.6 years (range 0.1-8.9 years), and one patient was lost to follow-up at 3.1 years.

There were no 30-day postoperative deaths. One patient died of pneumonia at 34 days after treatment. The median interval from treatment to wound resolution was 5 days for the entire series and was significantly shorter (2 days) for the surgically treated limbs than for those treated conservatively (38 days) (P=0.0001). The median interval from treatment to hospital discharge was also shorter for the surgically treated limbs (11 days) than for those treated conservatively (26 days) (P=0.025). There were no late recurrences, amputations, or graft infections. Cumulative 5-year survival for the entire series was 53%.

Surgical repair of groin lymphocutaneous fistulas and lymphoceles following synthetic graft placement is safe and durable. This approach yields significantly shorter intervals from treatment to wound resolution and requires a shorter postoperative hospitalization period than the conservative approach.