Sage Journals: Discover world-class research

Abstract

The purpose of this study was to evaluate the accuracy of radionuclide venography (RV) (with 99mTc-marked red blood cells) in the identification of incompetent perforating veins (IPVs) of the legs in patients with chronic venous insufficiency. After informed consent, RV, followed by contrast phlebography (CP), of the symptomatic leg was performed in 14 patients (20 legs). The results of RV were compared with those of CP, which was considered the standard technique in detecting IPVs of the leg. The sensitivity of RV was 92.3%; the specificity, 93.7%; the positive predictive value, 96%; the negative predictive value, 88.2%; and the accuracy, 92.9%. The authors conclude that RV has a high diagnostic accuracy in detecting IPVs of the leg.

Get full access to this article

View all access options for this article.

References

1. Lim L , Michuda M , Bergan JJ : The therapy of peripheral vascular ulcers—surgical management. Angiology 29:654-660, 1978.

2. Folse R , Alexander RH : Directional flow detection for localizing venous valvular incompetency. Surgery 67:114-121, 1970.

3. Lewis JD : Venous occlusion and incompetence in the lower limb. A study with a directional Doppler. In: Cardiovascular Applications of Ultrasound, ed. by Reneman RS . Amsterdam: Elsevier, 1974, pp 29-29,371-371.

4. Strandness DC Jr , Sumner DE : Ultrasonic velocity detector in the diagnosis of thrombophlebitis. Arch Surg 104:180-183, 1972.

5. Sumner DE , Baker DW , Strandness DC Jr : The ultrasonic velocity detector in a clinical study of venous disease. Arch Surg 97:75-80, 1968.

6. O'Donnel TF , Burand KG , Clemenson G , et al: Doppler examination vs clinical and phlebographic detection of the location of incompetent perforating veins. Arch Surg 112:31-35, 1977.

7. Rosfors S , Bygdeman S , Nordstrom E : Assessment of deep venous incompetence: A prospective study comparing duplex scanning with descending phlebography. Angiology 6:463-468, 1990.

8. Gomes AS , Webber MM , Buffkin D : Contrast venography vs radionuclide venography: A study of discrepancies and their possible significance. Nucl Med 142:719-728, 1982.

9. Leclerc JR , Wolfon C , Arzoumanian A , et al: Technetium-99m red blood cell venography in patients with clinically suspected deep vein thrombosis: A prospective study. J Nucl Med 29:1498-1506, 1988.

10.

10. Giordano A , Muzi M , D'Antini P . et al: Phleboscintigraphic detection of incompetent perforating veins to guide the surgical treatment of venous stasis ulceration. Radiol Diagn 34:370-374, 1993.

11.

11. Lisbona R : Radionuclide blood-pool imaging in the diagnosis of deep-vein thrombosis of the leg. In: Nuclear Medicine Annual, ed. by Freeman LM , Weissmann HS . New York: Raven Press, 1986, pp 161-193.

12.

12. Jamieson WG : State of the art of venous investigation and treatment. Can J Surg 36:119-128, 1993.

13.

13. Ryo UY , Colombetti LG , Polin SG , et al: Radionuclide venography: Significance of delayed washout; visualization of the saphenous system. J Nucl Med 17:590-595, 1976.

14.

14. Ryo UY , Qazi M , Srikantaswamy S , et al: Radionuclide venography: Correlation with contrast venography. J Nucl Med 18:11-17, 1977.

15.

15. Vlahos L , Mac Donald AF , Causer DA : Combination of isotope venography and lung scanning. Br J Radiol 49:840-851, 1976.

16.

16. Ennies JT , Dowsett DJ : Vascular Radionuclide Imaging. London: John Wiley & Sons, 1983, p 10-10.

17.

17. Giordano A , Muzi M , Massaro M , et al: Scintigraphic assessment of “effort” axillary-subclavian vein thrombosis. Clin Nucl Med 17:933-935, 1992.

18.

18. Silverstein AM , Turbiner EH : Technetium-99m red blood cell venography in upper extremity deep vein thrombosis. Clin Nucl Med 12:421-423, 1987.

Diagnostic Accuracy of Radionuclide Venography in the Assessment of Incompetent Perforating Veins of the Legs

Abstract

Get full access to this article

References