Fibrinogen and fibrinogen degradation product levels were estimated in 20 patients with thromboangiitis obliterans and compared with those in healthy smokers and patients with other peripheral vascular diseases. The presence of increased fibrinogen levels in patients with thromboangiitis obliterans raises the possibility of its being a risk factor in the pathogenesis of Buerger's disease.
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References
1.
Kannel WR, Agostino Rbd, Belanger AJ: Fibrinogen, cigarette smoking, and risk of cardiovascular diseases: Insights from the Framingham study. Am Heart J113:1006-1010, 1987.
2.
Meade TW, Chakrabarti R., Haines AP, et al: Haemostatic function and cardiovascular death; early results of a prospective study. Lancet1:1050-1054, 1980.
3.
Wilhelmsen L. , Svandsudd MD, Korson-Bentsen, et al: Fibrinogen as a risk factor for stroke and myocardial infarction. N Engl J Med311:501-505, 1984.
4.
Stone MC, Thorp JM: Plasma fibrinogen—a major coronary risk factor. J R Coll Gen Pract35:565-569, 1985.
Burch GE, De Pasquale ND: Editorial: Haematocrit, blood viscosity and myocardial infarction . Am J Med32:161-163, 1962.
7.
Wells RE, Merrill EW: Editorial: The variability of blood viscosity. Am J Med31:505-509, 1961.
8.
Gulati SM, Saha SM, Thusoo TK, et al: Immunological studies in thromboangiitis obliterans (Buerger's disease). J Surg Res27:287-292, 1979.
9.
Gulati SM, Madhra K., Nair SK, et al: Autoantibodies in thromboangiitis obliterans (Buerger's disease) . Angiology33:642-651, 1982.
10.
Gulati SM, Saha K., Kant L., et al: Significance of circulatory immune complexes in thromboangiitis obliterans. Angiology35:276-281, 1984.
11.
Gulati SM, Saha K., Agarwal V., et al: Profile of non-organ specific autoantibodies in thromboangiitis obliterans. Indian J Med Res80:228-231, 1984.
12.
Gulati SM, Sharma V., Agarwal V., et al: In vitro study of cell mediated immunity against tobacco in patients with thromboangiitis obliterans. Vasc Med3:35-40, 1985.
13.
Gulati SM, Agarwal V., Sharma V., et al: C3 complement and their breakdown product (C,d) in patients with thromboangiitis obliterans. Indian J Med Res84:607-611, 1986.
14.
Mathew JD, Hooper BM, Whittingham S., et al: Association of antibodies with smoking, cardiovascular morbidity and death in one Bussel town population. Lancet2:754-758, 1973.