A 53-year-old woman with deep venous thrombosis who was receiving IV heparin developed a large retroperitoneal hematoma, which compressed the femoral nerve. Symptoms of femoral neuropathy were present and an abdominal computed tomography scan confirmed the diagnosis. The development of retroperitoneal hematomas following heparin IV use is rare; however, physicians must be aware of this complication, which may determine definitive neurologic deficits.
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