HortonJD, CuthbertJA, SpadyDK. Dietary fatty acids regulate hepatic low-density lipoprotein (LDL) transport by altering LDL receptor protein and mRNA levels. J Clin Invest92: 743–749, 1993.
2.
SudhofTC, RussellDW, BrownMS, GoldsteinJL. 42-bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter. Cell48: 1061–1069, 1987.
3.
HortonJD, ShimomuraI.Sterol regulatory element-binding proteins: Activators of cholesterol and fatty acid biosynthesis. Curr Opin Lipidol10: 143–150, 1999.
4.
DeBose-BoydRA, BrownMS, LiWP, NohturfftA, GoldsteinJL, EspenshadePJ. Transport-dependent proteolysis of SREBP: Relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi. Cell99: 703–712, 1999.
5.
HortonJD, ShimomuraI, BrownMS, HammerRE, GoldsteinJL, ShimanoH.Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. J Clin Invest101: 2331–2339, 1998.
6.
WorgallTS, SturleySL, SeoT, OsborneTF, DeckelbaumRJ. Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element-binding protein. J Biol Chem273: 25537–25540, 1998.
7.
YahagiN, ShimanoH, HastyAH, Amemiya-KudoM, OkazakiH, TamuraY, IizukaY, ShionoiriF, OhashiK, OsugaJ, HaradaK, GotodaT, NagaiR, IshibashiS, YamadaN.A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids. J Biol Chem274: 35840–35844, 1999.
8.
XuJ, NakamuraMT, ChoHP, ClarkeSD. Sterol regulatory element binding protein-1 expression is suppressed by dietary polyunsaturated fatty acids: A mechanism for the coordinate suppression of lipogenic genes by polyunsaturated fats. J Biol Chem274: 23577–23583, 1999.
9.
JohnsonRA, WorgallTS, PengS, HamiltonJA, DeckelbaumRJ. Free fatty acids enhance cholesterol movement between model membranes. FASEB J14: A229, 2000.
HudginsLC, HellersteinMK, SeidmanCE, NeeseRA, TremaroliJD, HirschJ.Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects. J Lipid Res41: 595–604, 2000.
14.
HudginsLC, HellersteinM, SeidmanC, NeeseR, DiakunJ, HirschJ.Human fatty acid synthesis is stimulated by a eucaloric low-fat, high-carbohydrate diet. J Clin Invest97: 2081–2091, 1996.
15.
StampferMJ, HuFB, MansonJE, RimmEB, WilletWC. Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med343: 16–22, 2000.