Clinical Testing of Supplementation Therapy in Early Stage Breast Cancer: Pitfalls and Opportunities

1. Labriola D , Livingston R . Possible interactions between dietary antioxidants and chemotherapy . Oncology (Huntingt). 1999; 13: 1003-1008 .

2. Prasad KN , Cole WC , Kumar B , et al. Scientific rationale for using high-dose multiple micronutrients as an adjunct to standard and experimental cancer therapies . J Am Coll Nutr. 2001;20 (5 Suppl): 450S-463S .

3. Lockwood KS , Moesgaard S , Folkers K , et al . Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10 . Biochem Biophys Res Commun. 1994;199: 1504-1508 .

4. Lockwood KS , Moesgaard S , Yamamoto T , et al. Progress on therapy of breast cancer with vitamin Q10 and the regression of metastases . Biochem Biophys Res Commun. 1995;212: 172-177 .

5. Levi F , Pasche C , Lucchini F , La Vecchia C. Dietary intake of selected micronutrients and breast-cancer risk . Int J Cancer. 2001;91: 260-263 .

6. Garland M , Willett WC , Manson JE , Hunter DJ. Antioxidant micronutrients and breast cancer . J Am Coll Nutr. 1993;12: 400-411 .

7. Patterson RE , White E , Kristal AR , et al. Vitamin supplements and cancer risk: the epidemiologic evidence . Cancer Causes Control. 1997;8: 786-802 .

8. Early Breast Cancer Trialists' Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomised trials . Lancet. 1998;351: 1451-1467 .

9. Early Breast Cancer Trialists' Collaborative Group. Polychemotherapy for early breast cancer: an overview of the randomised trials . Lancet. 1998;352: 930-942 .

10. Melisko M , Hassin F , Metzroth L , et al. Physician and patient barriers to breast cancer clinical trials . Breast Cancer Res Treat. 2002;76(Suppl 1): S86 (Abstract #317).