Continuous Glucose Monitoring and Diabetic Foot Ulcers: Is it Time to Walk in Range? A Brief Narrative Review

Abstract

Diabetic foot ulcers (DFUs) are a serious and common complication of diabetes mellitus (DM), contributing substantially to patient morbidity, reduced quality of life, and healthcare costs. Accumulating evidence suggests that both low and high blood glucose may delay wound healing and increase mortality. Continuous glucose monitoring (CGM) in people with DM is known to improve glycaemic control compared with self-monitoring of blood glucose. This narrative review summarises current evidence on the role of CGM and CGM-derived metrics, such as time in range (TIR), in DFU management. Emerging evidence suggests that optimising glycaemic control with CGM sensors in patients with DFUs may be essential to promote wound healing and, ultimately, reduce the risk of amputations. Accordingly, CGM emerges as a promising tool to improve DFUs outcomes. Well-designed clinical trials are now needed to confirm these findings and to provide guidelines for everyday clinicians.