An increased extracellular water/intracellular water (ECW/ICW) ratio determined by bioimpedance has been related to mortality in patients undergoing hemodialysis. We aimed to evaluate the impact of body water distribution in patients with diabetes-related foot ulcers. Seventy-six patients were evaluated with bioimpedance, handgrip strength, and laboratory examinations. The ECW/ICW ratio is a prognostic factor for early mortality.
TianJPWangHDuFHWangT. The standard deviation of extracellular water/intracellular water is associated with all-cause mortality and technique failure in peritoneal dialysis patients. Int Urol Nephrol. 2016;48(9):1547-1554.
2.
KimEJChoiMJLeeJH, et al.Extracellular fluid/intracellular fluid volume ratio as a novel risk indicator for all-cause mortality and cardiovascular disease in hemodialysis patients. PLoS One. 2017;12(1):e0170272.
3.
ChenWGuoLJWangT. Extracellular water/intracellular water is a strong predictor of patient survival in incident peritoneal dialysis patients. Blood Purif. 2007;25(3):260-266.
4.
den DekkerADavisFMKunkelSLGallagherKA. Targeting epigenetic mechanisms in diabetic wound healing. Transl Res. 2019;204:39-50.
5.
LauwersPHendriksJMHVan BouwelS, et al.Malnutrition according to the 2018 GLIM criteria is highly prevalent in people with a diabetic foot ulcer but does not affect outcome. Clin Nutr ESPEN. 2021;43:335-341.
6.
Ignacio de UlibarriJGonzalez-MadronoAde VillarNG, et al.CONUT: A tool for controlling nutritional status. First validation in a hospital population. Nutr Hosp. 2005;20(1):38-45.
7.
LeveyASStevensLASchmidCH, et al.A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604-612.
8.
SchoberPBoerCSchwarteLA. Correlation coefficients: appropriate use and interpretation. Anesth Analg. 2018;126(5):1763-1768.
9.
ChengLTTangWWangT. Strong association between volume status and nutritional status in peritoneal dialysis patients. Am J Kidney Dis. 2005;45(5):891-902.
10.
HiokaAAkazawaNOkawaNNagahiroS. Increased total body extracellular-to-intracellular water ratio in community-dwelling elderly women is associated with decreased handgrip strength and gait speed. Nutrition. 2021;86:111175.
11.
Aragon-SanchezJViquez-MolinaGLopez-ValverdeMERojas-BonillaJM. Severe diabetic foot infections without systemic inflammatory response syndrome: prospective validation of a new category. Wound Repair Regen. 2022;30(5):553-559.
12.
ChenWChenKXuZ, et al.Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio predict mortality in patients with diabetic foot ulcers undergoing amputations. Diabetes Metab Syndr Obes. 2021;14:821-829.
13.
RoglerGRosanoG. The heart and the gut. Eur Heart J. 2014;35(7):426-430.