Macrophage Activation Dysfunction in Impaired Wound Healing

Abstract

Get full access to this article

View all access options for this article.

References

Singh

Halder

Menon

. Meta-analysis of randomized controlled trials on hydrocolloid occlusive dressing versus conventional gauze dressing in the healing of chronic wounds. Asian J Surg. 2004;27:326-332.

Posnett

Franks

. The burden of chronic wounds in the UK. Nurs Times. 2008;104(3):44-45.

Broughton

2nd Janis

Attinger

. The basic science of wound healing. Plast Reconstr Surg. 2006;117(7 suppl);12S-34S.

Roeckl-Wiedmann

Bennett

Kranke

. Systematic review of hyperbaric oxygen in the management of chronic wounds. Br J Surg. 2005;92:24-32.

Falanga

. The chronic wound: impaired healing and solutions in the context of wound bed preparation. Blood Cells Mol Dis. 2004;32:88-94.

Chen

Mandelin

. Regulation of macrophage activation. Cell Mol Life Sci. 2003;60:2334-2346.

Gordon

. Alternative activation of macrophages. Nat Rev Immunol. 2003;3:23-35.

Deonarine

Panelli

Stashower

. Gene expression profiling of cutaneous wound healing. J Transl Med. 2007;5:11.

Abd-El-Aleem

Ferguson

Appleton

. Expression of nitric oxide synthase isoforms and arginase in normal human skin and chronic venous leg ulcers. J Pathol. 2000;191:434-442.

10.

Goren

Müller

Schiefelbein

. Systemic anti-TNFα treatment restores diabetes-impaired skin repair in ob/ob mice by inactivation of macrophages. J Invest Dermatol. 2007;127:2259-2267.

11.

Seno

Miyoshi

Brown

Geske

Colonna

Stappenbeck

. Efficient colonic mucosal wound repair requires Trem2 signaling. Proc Natl Acad Sci U S A. 2009;106:256-261.

12.

Portera

Love

Memore

. Effect of macrophage stimulation on collagen biosynthesis in the healing wound. Am Surg. 1997;63:125-131.

13.

Zuloff-Shani

Kachel

Frenkel

Orenstein

Shinar

Danon

. Macrophage suspensions prepared from a blood unit for treatment of refractory human ulcers. Transfus Apher Sci. 2004;30:163-167.

14.

Deiters

Barsig

Tawil

Mühlradt

. The macrophage-activating lipopeptide-2 accelerates wound healing in diabetic mice. Exp Dermatol. 2004;13:731-739.

15.

Underhill

Ozinsky

Hajjar

. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature. 1999;401:811-815.

16.

Zhang

Shi

. Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing. Stem Cells. 2010;28:1856-1868.