The treatment of chronic skin ulcers with exposed bone in the lower extremity is difficult. The development of topical negative pressure (TNP) technology and microsurgical techniques have achieved good clinical results in the repair of such ulcers. Between January 2007 and March 2012, TNP combined with flap transfer was applied to repair lower-limb skin and soft-tissue defects associated with exposed bone in 22 cases at our hospital, and good results were achieved that are reported herein.
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