Despite declines in smoking prevalence, some populations represent significant challenges to tobacco cessation programs, including smokers with psychiatric comorbidity and/or weight concerns. Few studies have found effective interventions for tobacco cessation or addressed the prevalence of smoking-related concerns in psychiatric populations. The side effects of many psychotropic medications, decreased participation in physical activity, and weight gain following cessation suggest that postcessation weight concerns and actual weight gain may be significant barriers to cessation as well. Therefore, serial interventions, rather than simultaneous ones, seem well suited to address these issues. This case study represents the piloting of serial cessation and postcessation weight gain prevention interventions in a female diagnosed with paranoid schizophrenia. Results suggested that the serial implementation of cognitive-behavioral interventions can be effective in promoting tobacco cessation in individuals with co-occurring disorders.
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