Retraction: microRNA-195 Promotes Small Cell Lung Cancer Cell Apoptosis via Inhibiting Rap2C Protein-Dependent MAPK Signal Transduction

At the request of Sage and the Journal Editor, the following article has been retracted:

Tong J, Lu J, Yin Y, Wang Y, Zhang K. microRNA-195 Promotes Small Cell Lung Cancer Cell Apoptosis via Inhibiting Rap2C Protein-Dependent MAPK Signal Transduction. Technol. Cancer Res. Treat. 2020;19. doi: 10.1177/1533033820977546

Sage was made aware of concerns raised on PubPeer regarding the following figures in the article:

Figure 4B GAPDH (Control vs. Rap2C blot) appears highly similar to Figure 4F SMAD1 (Sh-NEAT1+NC vs. Sh-NEAT1+minics) in another publication¹

Figure 2C Control appears highly similar to Figure 3B Atr-III H in another publication²

The authors did not respond to requests for comments on these similarities.

Due to unresolved concerns about image integrity that call into question the validity of the findings, this article has been retracted.

The authors did not respond to the decision to retract.

References:

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Meng, Y., Hao, Z., Zhang, H., Bai, P., Guo, W., Tian, X., & Xu, J. lncRNA NEAT1/miR-495-3p regulates angiogenesis in burn sepsis through the TGF-β1 and SMAD signaling pathways. Immunity, Inflammation and Disease. 2023; e758. https://doi.org/10.1002/iid3.758

2.

Fu, J-D., Gao, C-H., Li, S-W., Tian, Y., Li, S-C., Wei, Y-E., & Xian, L-W. Atractylenolide III alleviates sepsis-mediated lung injury via inhibition of FoxO1 and VNN1 protein. Acta Cirurgica Brasileira. 2021; 36(8). https://doi.org/10.1590/ACB360802