Retraction notice: “MicroRNA-199a Inhibits Cell Proliferation,Migration,and Invasion and Activates AKT/mTOR Signaling Pathway by Targeting B7-H3 in Cervical Cancer”

At the request of Sage and the Executive Editor, the following article has been retracted:

Yang X, Feng K-X, Li H, Wang L, Xia H. MicroRNA-199a Inhibits Cell Proliferation, Migration, and Invasion and Activates AKT/mTOR Signaling Pathway by Targeting B7-H3 in Cervical Cancer. Technology in Cancer Research & Treatment. 2020;19. doi:10.1177/1533033820942245.

Sage was made aware of a PubPeer post that highlights the following concerns in this article.:

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Fig 3B GAPDH panel appears to be highly similar to Fig 5B AKT panel

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Fig 6E mTOR panel appears to be highly similar to Fig 5E mTOR panel in a previously published article by a different group of authors.¹

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Fig 4 miR-NC-vector HeLa panel appears to be highly similar to Fig 2 GT3TKB LV3-NC panel in a previously published article by a different group of authors.¹

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Fig 4 miR-NC-B7H3 HeLa panel appears to be highly similar to Fig 2 miR-375-inhibitors panel in a previously published article by a different group of authors.¹

The authors have been unresponsive to the journal’s requests for comment or raw, underlying images.

Due to unresolved concerns about image integrity, that call into question the validity of the findings, the Executive Editor retracts the article.

The authors did not respond to the final notice.

References-

1. Yuan K-T, Li B-X, Yuan Y-J, et al. Deregulation of MicroRNA-375 Inhibits Proliferation and Migration in Gastric Cancer in Association With Autophagy-Mediated AKT/mTOR Signaling Pathways. Technology in Cancer Research & Treatment. 2018;17. doi:10.1177/1533033818806499