Population-based studies have revealed differences in the preva lence of lower extremity arterial occlusive disease between males and females. Recent studies have begun to unravel the etiology of these gender-based differ ences. Nonetheless, the morbidity of lower extremity arterial disease may be severe and is similar for both genders. Recent studies, however, have revealed gender based bias in treatment patterns for arterial disease of the lower extrem ities. This review addresses the impact of gender on the prevalence, morbidity, and management of lower extremity atherosclerosis. A critical review of the surgical literature reveals that surgical management of infrainguinal occlusive disease offers females patients the same benefits and limitations as for male patients.
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