Liver Transplantation Using Graft From a Donor With Aplastic Anemia

Abstract

Liver transplantation (LT) is a life-saving procedure in patients with end-stage liver disease. The number of patients in the waiting list for LT has steadily increased over time, so removing liver from deceased donors with unusual disorders could possibly be used for transplantation. We describe a case of LT from a donor with “aplastic anemia” to a patient with liver failure due to hepatitis C. Aplastic anemia is a syndrome of bone marrow failure. Aplastic anemia is one of the most common conditions linked to transfusion dependence, and long-term repeated transfusion inevitably results in iron overload. Also iron is a cofactor that influences the severity and progression of nonhemochromatic liver diseases, especially steatohepatitis and viral hepatitis. The aim of this report is to highlight the posttransplant findings of the recipient, with specific emphasis on the graft function. Our findings provide insights into the clinical implications of LT using graft with this rare disorder.