The problem and the solution. Mergers and acquisitions have become one of the most well-known business strategies in the global economy. Increasing market share, gaining core capabilities, and accessing more capital at lower cost are results from a successful and effective merger and acquisition. However, emphasizing business strategies and financial issues is not enough. Organizations also need to focus on their human resources in mergers and acquisitions. Knowledge and knowledge management as a soft side of mergers and acquisitions play a vital role. Having a better understanding of the relationship between knowledge management and mergers and acquisitions will help the combined organization succeed in mergers and acquisitions and sustain competitive advantage.