The biocompatibility of the Ti6Al4V alloy is well known, due to its non-magnetic behaviour, low density, lightweight design and corrosion resistance. Nevertheless, the Ti6A14V alloy has many shortcomings, including a lack of antimicrobial activity, which raises the risk of implant failure and cellular toxicity. Considering this, research is being done to determine whether the cefotaxime (CTX) may efficiently suppress the corrosion of Ti6A14V alloy in artificial saliva solution using potentiodynamic polarisation curves, open-circuit potential and electrochemical impedance spectroscopy. As the inhibitor's concentration rose, so did the inhibition efficiency, achieving 82.0% at 600 ppm. The investigated CTX functions as a mixed-type inhibitor. Additionally, the adsorption of the CTX inhibitor followed the Langmuir isotherm. The temperature increased the corrosion current (Icorr) and the corrosion rate. The barrier layer covering the surface of the Ti alloy was verified by the surface characterisation investigation using scanning electron microscope/energy dispersive X-ray. The predominant adsorption mechanism for CTX was physisorption. Moreover, quantum calculations have been carried out, such as density functional theory. Also, Monte Carlo simulations were used to comprehend the tested inhibitor's adsorption behaviour.
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