Salmonella typhi is a rare cause for infective endocarditis. Seventy five per cent of cases suffering from this condition have an underlying cardiac abnormality such as rheumatic heart disease or congenital heart defect. We report a case of native tricuspid valve endocarditis due to Salmonella typhi. Organism was resistant to chloramphenicol, amoxycillin, moderately sensitive to ciprofloxacin and sensitive Ceftriaxone and Gentamicin. Patient improved with prolonged course of Ceftriaxone and Gentamicin therapy.
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