Vascular thrombosis associated with long-haul air travel has attracted considerable public attention. Most research has used case control studies where selection bias can reduce reliability, but RCTs would be impracticle. Symptomatic DVT probably occurs up to 0·28% of passengers, and asymptomatic DVT in up to 10·3%. Pulmonary embolous is the feared complication. Immobility is probably a main factor in flight DVT, but other unknown factors may also be important. Passengers with risk-factors for DVT should consider prophylaxix; LMWH for those at high risk, and compression stockings in all risk groups.
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