Research misconduct and public trust

1 Hwang WS YJ Ryu Park JH Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst. Science 2004; 303(5664):1669–74.

2 Hwang WS SI Roh Lee BC Patient-specific embryonic stem cells derived from human SCNT blastocysts. Science 2005; 308(5729):1777–83.

3 Kennedy D. Editorial retraction. Science 2006; 311:335.

4 Lee BC MK Kim Jang G Dogs cloned from adult somatic cells. Nature 2005; 436(7051):64.

5 Dalton R. Obesity expert owns up to million-dollar crime. Nature 2005; 434:424.

6 Horton R. Retraction – Non-steroidal anti-inflammatory drugs and the risk of oral cancer: a nested case-control study. Lancet 2006; 367:382.

7 Curfman GD S Morrissey Drazen JM. Expression of concern: Sudbø J DNA content as a prognostic marker in patients with oral leukoplakia. N Engl J Med 2001; 344:1270–8; Sudbø J The influence of resection and aneuploidy on mortality in oral leukoplakia. N Engl J Med 2004; 350:1405–13.

8 Couzin J Fraud Upends Oral Cancer Field Schirber M. Casting Doubt on Prevention T rial. Science 2006; 311:448–9.

9 Farthing MJG. ‘Publish, and be damned … ‘ The road to research misconduct. J R Coll Physicians Edinb 2004; 34(4):301–4.

10 Smith R. Research misconduct; the poisoning of the well. J Roy Soc Med 2006; 99:232–7.

11Royal College of Physicians of London. Fraud and misconduct in medical research: causes, investigation and prevention. London: Royal College of Physicians of London; 1991.

12Joint Consensus Conference on Misconduct in Biomedical Research; Nimmo W, editor. Papers from a conference held in the Royal College of Physicians of Edinburgh on 28 and 29 October 1999. Proc R Coll Physicians Edinb 2000;30: Suppl 7 Note: Conference was in 1999 but this was published in 2000.

13 Wade N. Lowering expectations at science’s frontier. NY Times 2006 Jan 15.

14 Campion EW. Medical Research and the News Media. N Engl J Med 2004; 351:2436–7.

15Behind the Medical Headlines. Edinburgh: Royal College of Physicians of Edinburgh; 2006. Accessed 24.05.06. Available from: http://www.behindthemedicalheadlines.com

16 Smith R. Peer review: a flawed process at the heart of science and journals. J Roy Soc Med 2006; 99:178–82.

17See Medibytes this issue at 127.

18Medibytes. J R Coll Physicians Edinb 2006; 36:43.

19In brief. BMJ 2006;332:194.

20Royal College of Physicians of London. Doctors in society: medical professionalism in a changing world. London: Royal College of Physicians of London; 2005.