ALLOXAN DIABETES

1 Lenzen S Panten U. Alloxan: history and mechanism of action. Diabetologia 1988; 31:337–42.

2 Jörns A R Munday Tiedge M Comparative toxicity of alloxan, N-alkylalloxans and ninhydrin to isolated pancreatic islets in vitro. J Endocrinology 1997; 155:283–93.

3 Muir R Browning CH. Obituary notices of deceased members; John Shaw Dunn. J Path Bact 1944; 58:577–92.

4Shaw Dunn J, Sheehan HL, McLetchie NGB. Necrosis of the islets of Langerhans produced experimentally. Lancet 1943; 244:484–7.

5 Sheehan HL McLetchie NGB. Simmonds’s disease due to post-partum necrosis. J Obst Gyn B E 1943; 50:27–36.

6 Gillespie M JSF Niven Shaw Dunn J. The renal lesions in cases of ‘crush’ syndrome. J Path Bact 1941; 53:158–9.

7 Bywaters EGL. 50 years on: the crush syndrome. BMJ 1990; 301:1412–15.

8 Munger BL. Morphological characterization of islet-cell diversity. In: Cooperstein SJ and Watkins D, editors. The islets of Langerhans. New York: Academic Press; 1981; 30–4.

9Figure 21·12. In: Junqueira LC, Carneiro J, Kelly RO, editors. Basic Histology. Stanford: Appleton and Lange; 1998; 396. Also, personal communication, Carneiro J, 25 October 2000.

10Shaw Dunn J. An experimental lesion of the pancreatic islets. Surgo (Glasgow University Medical Journal). 1943; 9:32–4.

11Shaw Dunn J, McLetchie NGB. Alloxan diabetes in the rat. Proc Path Soc Gt Br London; March1943.

12Shaw Dunn J, McLetchie NGB. Experimental alloxan diabetes in the rat. Lancet 1943; 11:384–6.

13Shaw Dunn J, Kirkpatrick J, McLetchie NGB Necrosis of the islets of Langerhans produced experimentally. J Path Bact 1943; 45:245–57.

14Shaw Dunn J, Duffy E, Gilmour M Experimental isletcell necrosis; alloxan diabetes in the rabbit. Proc Path Soc Gt Brit. Manchester; July 1943.

15 Hughes H LL Ware Young FG. Diabetogenic action of alloxan. Lancet 1944; 1:148–50.

16Shaw Dunn J, Duffy E, Gilmour MK Further observations on the effects of alloxan on pancreatic islets. J Physiol 1944; 103:233–43.

17 Brunschwig A J Allen Goldner MG JAMA 1943; 122:96.

18 Goldner MG Gomori G. Alloxan diabetes in the dog. Endocrinology 1943; 35:241–68.

19 Bailey CC Bailey OT. The production of diabetes mellitus in rabbits with alloxan. JAMA 1943; 122:1165–6.

20 Gomori G Goldner MG. Production of diabetes mellitus in rats with alloxan. JAMA 1943; 123:287–90.

21 Cooperstein SJ Watkins D. Alloxan. In: Cooperstein SJ, Watkins D, editors. The islets of Langerhans. New York: Academic Press; 1981; 388–411.

22Ibid., Streptozotocin, 411–18.

23 Webb JL. Alloxan. In: Webb JL, editor. Enzyme and metabolic inhibitors, Vol. 3. New York: Academic Press; 1966; 367–419.

24 Wang Z Gleichen H. GLUT2 in pancreatic islets: crucial target molecule in diabetes induced with multiple low doses of streptozotocin in mice. Diabetes 1998; 47:50–6.

25 Elsner M B Guldbankke Tiedge M Relative importance of transport and alkylation for pancreatic B-cell toxicity of streptozotocin. Diabetologia 2000; 43:1528–33.