Refractory hypoglycaemia in diabetes: a quinolone link

Abstract

Quinolones are commonly used medications due to their broad spectrum of action and high oral bioavailability. However, clinicians should be aware of potential toxicities including hypoglycaemia and cardiac rhythm disturbances. We present a case of quinolone induced severe refractory hypoglycaemia in a diabetic patient on sulphonylurea. Clinicians should educate patients about the possible hypoglycaemic effects of quinolones and assess the risk benefit ratio prior to initiating treatment with this group of drugs.