Nathan DM, Buse JB, Davidson MB et al. Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. Diabetologia2006;49:1711-21.
2.
National Institute for health and Clinical Excellence.Clinical Guideline G. Type 2 diabetes: the management type 2 diabetes (update) . NICE. London2008. www.nice.org.uk (Accessed May 2008)
3.
UK Prospective Diabetes Study (UKPDS) Group.Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet1998;352:854-65.
4.
Bailey CJ, Turner RCMetformin. N Engl J Med1996; 334:574-9.
5.
Wiernsperger NF50 years later: is metformin a vascular drug with antidiabetic properties?Br J Diabetes Vasc Dis2007;7:204-10.
6.
Zhou G., Myers R., Li Y. et al. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest2001;108:1167-74.
7.
Glucophage.Summary of Product Characteristics , 2004.
8.
Glucophage SRSummary of Product Characteristics, 2006.
9.
Feher MD, Al-Mrayat M., Brake J., Leong KSTolerability of prolonged release metformin (Glucophage SR) in individuals intolerant to standard metformin - results from four UK centres. Br J Diabetes Vasc Dis2007;7:22A5-8.
10.
Krentz AJ, Bailey CJType 2 diabetes in practice (2nd edn). Royal Society of Medicine Press, London, 2005, 206pp.
11.
Holstein A. , Stumvoll M.Contraindications can damage your health - is metformin a case in point?Diabetologia2005;48:2454-9.
12.
Douek IF, Allen SE, Ewings P. et al. Continuing metformin when starting insulin in patients with type 2 diabetes: a double-blind randomised placebo-controlled trial. Diabetic Med2005; 22:634-40.
13.
Salpeter S. , Greyber E., Pasternak G., Salpeter E.Risk of fatal and non-fatal lactic acidosis with metformin use in type 2 diabetes mellitusCochrane Database Syst Rev CD002967.