Needle-based delivery systems suit the vast majority of people with type 1 and type 2 diabetes who require insulin. However, a small group may be better suited to a needle-free delivery system. In the UK, GPs can now prescribe, on the NHS, such a needle-free delivery system — sometimes called a jet injector. These devices are not necessarily pain free but they have a well-established history and offer patients and their healthcare professionals a credible alternative to a needle-based insulin injection.
Bremseth D., Pass F.Delivery of Insulin by jet injection: recent observationDiabetes Technol Ther2001;3:225-32.
2.
Strauss K., Gols H., Letondeur C., Matyjaszczyk M., Frid A.The Second Injection Technique Event (SITE) May 2000 Barcelona Spain. Prac Diabetes Inter2002;19(1):19. (Epidemiology of Insulin injection in Europe).
3.
Hanas R., Ludvigsson J.Experience of pain from insulin injections and needle phobia in young patients with IDDM. Pract Diabetes Inter1997 ; 14(4):95-9.
4.
http://www.needlestickforum.net/ accessed 11th January 2004.
5.
Hamilton J.Needle phobia: A neglected diagnosis. J Fam Prac1995; 41:169-75.
6.
Zambanini A. , Feher M.Needle Phobia in Type 1 Diabetes . Diabet Med1997;14:321-3.
7.
Stephens JW, Butteriss D., Payne N., Barker SGE, Hurel SJSubcutaneous insulin without a needle: a pilot evaluation of the J-Tip® delivery system. Practical Diabetes International2003 ;20(2):47-50.
8.
Levine M.Can Needle-Free administration of vaccines become the norm in global immunization?Nat Med2003;9:99-103.
9.
http://www.insulinjet.com/technology/patterns.asp accessed 11th January 2004.
10.
Goodman & Gilman's.The pharmacological basis of therapeutics Edited by Hardman J. Limbird L. 10th Edition published 2001New York: McGraw Hill ISBN 0-07-135469-7 Page 1697.
11.
Schneider U. , Birnbacher R., Schober E.Painfulness of needle and jet injection in children with diabetes mellitus: Euro J Paediatrics1994;153:409-10.
12.
Davidson's Principles and Practice of Medicine. Editors Christopher Haslett, Edwin Chilvers, Nicholas Boon and Nicki College.19th Edition (50th Anniversary edition) published 2002Edinburgh : Churchill Livingstone Page 661.
13.
Goodman & Gilman'sThe pharmacological basis of therapeutics Edited by Hardman J. Limbird L. 10th Edition published 2001New York: McGraw Hill ISBN 0-07-135469-7 Page 1696.
14.
Stewart NL, Darlow BAInsulin loss at the injection site in children with type 1 diabetes mellitus . Diabet Med1994;11:802-05.