Athorough clinical assessment and evaluation of foot perfusion is essential in managing diabetic foot disease. The treatment of macrovascular disease is key to reducing the high amputation rates seen in diabetic patients, particularly as small vessel dysfunction may make diabetic individuals more vulnerable to the effects of macrovascular, atherosclerotic disease. The clinical assessment remains paramount in the management of diabetic foot disease. The confounding effects of peripheral neuropathy on the symptoms and signs of lower limb arterial insufficiency can make assessment difficult. This article provides a resume of the clinical manifestation of lower limb ischaemia and neuropathy and the importance of accurate evaluation of the diabetic foot.
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