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Abstract

Coronary artery bypass graft (CABG) patients often have cerebrovascular disease and pre-operative brain magnetic resonance angiography (MRA) frequently reveals cerebral vasculature stenosis. This study was designed to investigate whether pre-operative MRA findings correlated with regional cerebral oxygen saturation (ScO₂) in 120 patients undergoing on-pump or off-pump CABG. Following MRA examination, patients were divided into six groups of 20 patients each based on MRA findings (no stenosis, mild stenosis or severe stenosis) and procedure (on-pump or off-pump CABG). Mean ScO₂ values over 3 min were determined at seven periods during surgery. Patients with severe cerebrovascular stenosis showed significantly lower ScO₂ than other groups during off-pump CABG. During on-pump CABG, ScO₂ decreased significantly during cardiopulmonary bypass in all groups and was significantly lower in the severe stenosis group. Pre-operative MRA and intra-operative ScO₂ monitoring may help to identify patients at increased risk of brain damage during or following CABG.

Keywords

Cerebrovascular disease On-pump coronary artery bypass graft Off-pump coronary artery bypass graft brain magnetic resonance angiography cerebral oxygen saturation Near-infrared spectroscopy

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Correlation between Pre-Operative Brain Magnetic Resonance Angiography Findings and Intra-Operative Cerebral Oxygen Saturation during Coronary Artery Bypass Graft Surgery

Abstract

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