BatainehA,Raij L.Angiotensin II, nitric oxide, and end-organ damage in hypertension. Kidney Int Suppl1998; 68: S14-9.
2.
Grant S., Griendling KKVascular effects of angiotensin II and AT1 receptor blockade. In: Epstein M and Brunner HR , eds. Angiotensin II Receptor Antagonists. Philadelphia: Hanley & Belfus, Inc . 2000; 235-56.
3.
Ishani A., Raij L.Hypertension, nitric oxide and end-organ damage. Curr Opin Nephrol Hyperten1999; 8: 237-41.
4.
Warnholtz A. , Nickenig G., Schulz E. et al. Increased NADHoxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the reninangiotensin system. Circulation1999; 99 (15): 2027-33.
5.
Griendling KK , Sorescu D., Ushio-Fukai M.NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res2000; 86(5): 494-501.
6.
Wolin MSInteractions of oxidants with vascular signaling systems. ArteriosclerThromb Vasc Biol2000; 20 (6): 1430-42.
7.
Ronson RS, Nakamura M.,Vinten-Johansen J.The cardiovascular effects and implications of peroxynitrite. Cardiovasc Res1999; 44 (1): 47-59.
8.
Wolin MS, Burke-Wolin TM, Mohazzab HKRoles for NAD(P)H oxidases and reactive oxygen species in vascular oxygen sensing mechanisms. Respir Physiol1999;115 (2): 229-38.
9.
Irani K.Oxidant signaling in vascular cell growth, death, and survival : a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling. Circ Res2000; 87 (3): 179-83.
10.
Ohara Y., Peterson TE, Harrison DGHypercholesterolemia increases endothelial superoxide anion production . J Clin Invest1993; 91 (6): 2546-51.
11.
Vasquez-Vivar J., Kalyanaraman B., Martasek P. et al. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci USA1998; 95 (16): 9220-5.
12.
Cosentino F. , Patton S., d'Uscio LV et al.Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats. J Clin Invest1998; 101 (7): 1530-7.
13.
Shinozaki K. , NishioY, OkamuraT et al. Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats. Circ Res2000; 87 (7): 566-73.
14.
Suzuki YJ, Forman HJ, Sevanian A.Oxidants as stimulators of signal transduction. Free Radic Biol Med1997; 22 (1-2): 26985.
15.
Sundaresan M., Yu ZX, Ferrans VJ, Irani K., Finkel T.Requirement for generation of H2O2 for platelet-derived growth factor signal transduction . Science1995; 270 (5234): 296-9.
16.
De Keulenaer GW, Chappell DC, Ishizaka N., Nerem RM, Alexander RW, Griendling KKOscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. Circ Res1998; 82 (10): 1094-101.
17.
Yeh LH, Park YJ, Hansalia RJ et al. Shear-induced tyrosine phosphorylation in endothelial cells requires Rac1-dependent production of ROS. Am J Physiol1999; 276 (4 Pt 1):C838-47.
18.
Rubanyi GM, Romero JC, Vanhoutte PMFlow-induced release of endothelium-derived relaxing factor. Am J Physiol1986; 250 (6 Pt 2): H1145-9.
19.
Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res1994; 74 (6): 1141-8.
20.
Jaimes EA, Galceran JM, Raij L. Angiotensin II induces superoxide anion production by mesangial cells . Kidney Int1998; 54 (3): 775-84.
21.
Berry C., Hamilton CA, Brosnan MJ et al. Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries. Circulation2000; 101 (18): 2206-12.
22.
Laursen JB, Rajagopalan S., Galis Z.,Tarpey M., Freeman BA, Harrison DGRole of superoxide in angiotensin II-induced but not catecholamine-induced hypertension. Circulation1997; 95 (3): 588-93.
23.
Heitzer T., Wenzel U., Hink U. et al. Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: evidence for an involvement of protein kinase C. Kidney Int1999; 55 (1): 252-60.
24.
Rajagopalan S. , Kurz S., Munzel T. et al.Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone . J Clin Invest1996; 97 (8): 1916-23.
25.
Nakane H., Miller FJ Jr., Faraci FM,Toyoda K., Heistad DDGene transfer of endothelial nitric oxide synthase reduces angiotensin II-induced endothelial dysfunction. Hypertension2000 ; 35 (2): 595-601.
26.
Baas AS, Berk BCDifferential activation of mitogen-activated protein kinases by H2O2 and O2- in vascular smooth muscle cells. Circ Res1995; 77 (1): 29-36.
27.
Ushio-Fukai M. , Alexander RW, Akers M., Griendling KK p38Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy. JBiol Chem1998; 273 (24): 15022-9.
28.
Yanagitani Y., Rakugi H., Okamura A. et al. Angiotensin II type 1 receptor-mediated peroxide production in human macrophages. Hypertension1999; 33 (1 Pt 2): 335-9.
29.
Scheidegger KJ, Butler S., Witztum JL. Angiotensin II increases macrophage-mediated modification of low density lipoprotein via a lipoxygenase-dependent pathway . J Biol Chem1997; 272 (34): 21609-15.
30.
Oyama J., Shimokawa H., Momii H. et al. Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo. J Clin Invest1998; 101 (10): 2207-14.
31.
Ferdinandy P., Danial H., Ambrus I., Rothery RA, Schulz R.Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure . Circ Res2000 ; 87 (3): 241-7.
32.
Ishiyama S. , Hiroe M., Nishikawa T. et al. Nitric oxide contributes to the progression of myocardial damage in experimental autoimmune myocarditis in rats. Circulation1997; 95 (2): 489-96.
33.
Fukai T., Siegfried MR, Ushio-Fukai M., Cheng Y., Kojda G., Harrison DGRegulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. J Clin Invest2000; 105 (11):1631-9.
34.
Drummond GR , Cai H., Davis ME, Ramasamy S., Harrison DGTranscriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide. Circ Res2000; 86 (3): 347-54.
35.
Landmesser UIF , McCann L., Fukai T., Somers MJ, Harrison DGUncoupling of endothelial nitric oxide synthase leads to increased vascular suproxide produciton in deoxycorticosterone acetate (DOCA)-salt induced hypertension. Circulation2000; 102 (18): (Abstract) II-61.
36.
Dimmeler S. , Rippmann V., Weiland U., Haendeler J., Zeiher AMAngiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide. Circ Res1997; 81 (6): 970-6.
37.
Yang Y., Loscalzo J.Regulation of tissue factor expression in human microvascular endothelial cells by nitric oxide. Circulation2000; 101 (18): 2144-8.
38.
Muller DN, Mervaala EM, Dechend R. et al. Angiotensin II (AT(1)) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy.Am JPathol2000; 157 (1):111-22.
39.
Ichiki T., Usui M., Kato M. et al. Downregulation of angiotensin II type 1 receptor gene transcription by nitric oxide. Hypertension1998; 31 (1 Pt 2): 342-8.
40.
Usui M., Egashira K., Kitamoto S. et al. Pathogenic role of oxidative stress in vascular angiotensin-converting enzyme activation in long-term blockade of nitric oxide synthesis in rats . Hypertension1999; 34 (4 Pt 1): 546-51.
Libby P.,Aikawa M., Kinlay S., Selwyn A., Ganz P.Lipid lowering improves endothelial functions. Int J Cardiol2000; 74 Suppl 1: S3-S10.
43.
Drexler H., Hornig B.Endothelial dysfunction in human disease.JMol Cell Cardiol1999; 31 (1):51-60.
44.
Oskarsson HJ , Heistad DDOxidative stress produced by angiotensin too. Implications for hypertension and vascular injury. Circulation1997; 95 (3): 557-9.
45.
Schiffrin EL , Deng LY, Larochelle P.Progressive improvement in the structure of resistance arteries of hypertensive patients after 2 years of treatment with an angiotensin I converting enzyme inhibitor. Comparison with effects of a beta-blocker. Am JHypertens1995 ; 8 (3): 229-36.
46.
Schiffrin EL , Deng LYComparison of effects of angiotensin I converting enzyme inhibition and beta-blockade for 2 years on function of small arteries from hypertensive patients. Hypertension1995 ; 25 (4 Pt 2): 699-703.
47.
Mancini GB, Henry GC, Macaya C. et al. Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease.The TREND (Trial on Reversing ENdothelial Dysfunction) Study. Circulation1996; 94 (3): 258-65.
48.
Chobanian AV , Haudenschild CC, Nickerson C., Drago R.Antiatherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit. Hypertension1990; 15 (3): 327-31.
49.
Varin R., Mulder P., Tamion F. et al. Improvement of endothelial function by chronic angiotensin-converting enzyme inhibition in heart failure : role of nitric oxide, prostanoids, oxidant stress, and bradykinin. Circulation2000; 102 (3): 351-6.
50.
Schiffrin EL , Hayoz D.Role of AT1 angiotensin receptors in vascular remodeling in hypertension. In: Epstein M and Brunner HR, ed. Angiotensin II Receptor Antagonists. Philadelphia: Hanley & Belfus, Inc. 2000: 279-94.
51.
Nishikawa K.Angiotensin AT1 receptor antagonism and protection against cardiovascular end-organ damage. J Hum Hypertens1998; 12 (5): 301-9.
52.
Schiffrin EL , Park JB, Intengan HD, Touyz RMCorrection of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan. Circulation2000; 101 (14): 1653-9.
53.
Nozawa Y., Matsuura N., Miyake H., Yamada S., Kimura R.Effects of TH-142177 on angiotensin II-induced proliferation, migration and intracellular signaling in vascular smooth muscle cells and on neointimal thickening after balloon injury. Life Sci1999; 64 (22): 2061-70.
54.
Prasad A., Tupas-Habib T., Schenke WH et al. Acute and chronic angiotensin-1 receptor antagonism reverses endothelial dysfunction in atherosclerosis. Circulation2000; 101 (20): 2349-54.
55.
Laufs U., La Fata V., Plutzky J., Liao JKUpregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors . Circulation1998; 97 (12): 1129-35.
56.
Vogel RACholesterol lowering and endothelial function. Am J Med1999; 107 (5):479-87.
57.
Tsao PS, Cooke JPEndothelial alterations in hypercholesterolemia: more than simply vasodilator dysfunction. J Cardiovasc Pharmacol1998; 32 (Suppl 3): S48-53.
58.
John S., Schmieder REImpaired endothelial function in arterial hypertension and hypercholesterolemia: potential mechanisms and differences.JHypertens2000; 18 (4): 363-74.
59.
Sen CK, Packer L.Antioxidant and redox regulation of gene transcription. FASEB J1996;10 (7): 709-20.
60.
Levine GN, Frei B., Koulouris SN, Gerhard MD, Keaney JF Jr.,Vita JAAscorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation1996; 93 (6): 1107-13.
61.
Ting HH,Timimi FK, Boles KS, Creager SJ, Ganz P., Creager MA. Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus. J Clin Invest1996; 97 (1):22-8.
62.
May JMHow does ascorbic acid prevent endothelial dysfunction?Free Radic Biol Med2000; 28 (9): 1421-9.
63.
Pearce KA, Boosalis MG,Yeager B.Update on vitamin supplements for the prevention of coronary disease and stroke . Am Fam Physician2000; 62 (6): 1359-66.
64.
Rumiantseva OI, Tutel'ian VA, Pogozheva AV, Askol'zina SE, Lysenkova SLBiologically active food supplements in comprehensive therapy of patients with ischemic heart disease and hypertension and the background of overweight. Vopr Pitan2000; 69 (1-2): 44-6.
65.
Barbacanne MA, Rami J., Michel JB et al. Estradiol increases rat aorta endothelium-derived relaxing factor (EDRF) activity without changes in endothelial NO synthase gene expression: possible role of decreased endothelium-derived superoxide anion production. Cardiovasc Res1999; 41 (3): 672-81.
66.
Nascimento CA, Kauser K., Rubanyi GMEffect of 17beta-estradiol in hypercholesterolemic rabbits with severe endothelial dysfunction. Am J Physiol1999; 276 (5 Pt 2): H1788-94.
