Review: Interaction among angiotensin II,nitric oxide and oxidative stress

BatainehA, Raij L. Angiotensin II, nitric oxide, and end-organ damage in hypertension. Kidney Int Suppl1998; 68: S14-9.

Grant S. , Griendling KK Vascular effects of angiotensin II and AT1 receptor blockade. In: Epstein M and Brunner HR , eds. Angiotensin II Receptor Antagonists. Philadelphia: Hanley & Belfus, Inc . 2000; 235-56.

Ishani A. , Raij L. Hypertension, nitric oxide and end-organ damage. Curr Opin Nephrol Hyperten1999; 8: 237-41.

Warnholtz A. , Nickenig G. , Schulz E. et al. Increased NADHoxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the reninangiotensin system. Circulation1999; 99 (15): 2027-33.

Griendling KK , Sorescu D. , Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res2000; 86(5): 494-501.

Wolin MS Interactions of oxidants with vascular signaling systems. ArteriosclerThromb Vasc Biol2000; 20 (6): 1430-42.

Ronson RS , Nakamura M. , Vinten-Johansen J. The cardiovascular effects and implications of peroxynitrite. Cardiovasc Res1999; 44 (1): 47-59.

Wolin MS , Burke-Wolin TM , Mohazzab HK Roles for NAD(P)H oxidases and reactive oxygen species in vascular oxygen sensing mechanisms. Respir Physiol1999;115 (2): 229-38.

Irani K. Oxidant signaling in vascular cell growth, death, and survival : a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling. Circ Res2000; 87 (3): 179-83.

Ohara Y. , Peterson TE , Harrison DG Hypercholesterolemia increases endothelial superoxide anion production . J Clin Invest1993; 91 (6): 2546-51.

Vasquez-Vivar J. , Kalyanaraman B. , Martasek P. et al. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci USA1998; 95 (16): 9220-5.

Cosentino F. , Patton S. , d'Uscio LV et al.Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats. J Clin Invest1998; 101 (7): 1530-7.

Shinozaki K. , NishioY, OkamuraT et al. Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats. Circ Res2000; 87 (7): 566-73.

Suzuki YJ , Forman HJ , Sevanian A. Oxidants as stimulators of signal transduction. Free Radic Biol Med1997; 22 (1-2): 26985.

Sundaresan M. , Yu ZX , Ferrans VJ , Irani K. , Finkel T. Requirement for generation of H2O2 for platelet-derived growth factor signal transduction . Science1995; 270 (5234): 296-9.

De Keulenaer GW , Chappell DC , Ishizaka N. , Nerem RM , Alexander RW , Griendling KK Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. Circ Res1998; 82 (10): 1094-101.

Yeh LH , Park YJ , Hansalia RJ et al. Shear-induced tyrosine phosphorylation in endothelial cells requires Rac1-dependent production of ROS. Am J Physiol1999; 276 (4 Pt 1):C838-47.

Rubanyi GM , Romero JC , Vanhoutte PM Flow-induced release of endothelium-derived relaxing factor. Am J Physiol1986; 250 (6 Pt 2): H1145-9.

Griendling KK , Minieri CA , Ollerenshaw JD , Alexander RW. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res1994; 74 (6): 1141-8.

Jaimes EA , Galceran JM , Raij L. Angiotensin II induces superoxide anion production by mesangial cells . Kidney Int1998; 54 (3): 775-84.

Berry C. , Hamilton CA , Brosnan MJ et al. Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries. Circulation2000; 101 (18): 2206-12.

Laursen JB , Rajagopalan S. , Galis Z. , Tarpey M. , Freeman BA , Harrison DG Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension. Circulation1997; 95 (3): 588-93.

Heitzer T. , Wenzel U. , Hink U. et al. Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: evidence for an involvement of protein kinase C. Kidney Int1999; 55 (1): 252-60.

Rajagopalan S. , Kurz S. , Munzel T. et al.Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone . J Clin Invest1996; 97 (8): 1916-23.

Nakane H. , Miller FJ Jr. , Faraci FM , Toyoda K. , Heistad DD Gene transfer of endothelial nitric oxide synthase reduces angiotensin II-induced endothelial dysfunction. Hypertension2000 ; 35 (2): 595-601.

Baas AS , Berk BC Differential activation of mitogen-activated protein kinases by H2O2 and O2- in vascular smooth muscle cells. Circ Res1995; 77 (1): 29-36.

Ushio-Fukai M. , Alexander RW , Akers M. , Griendling KK p38Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy. JBiol Chem1998; 273 (24): 15022-9.

Yanagitani Y. , Rakugi H. , Okamura A. et al. Angiotensin II type 1 receptor-mediated peroxide production in human macrophages. Hypertension1999; 33 (1 Pt 2): 335-9.

Scheidegger KJ , Butler S. , Witztum JL. Angiotensin II increases macrophage-mediated modification of low density lipoprotein via a lipoxygenase-dependent pathway . J Biol Chem1997; 272 (34): 21609-15.

Oyama J. , Shimokawa H. , Momii H. et al. Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo. J Clin Invest1998; 101 (10): 2207-14.

Ferdinandy P. , Danial H. , Ambrus I. , Rothery RA , Schulz R. Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure . Circ Res2000 ; 87 (3): 241-7.

Ishiyama S. , Hiroe M. , Nishikawa T. et al. Nitric oxide contributes to the progression of myocardial damage in experimental autoimmune myocarditis in rats. Circulation1997; 95 (2): 489-96.

Fukai T. , Siegfried MR , Ushio-Fukai M. , Cheng Y. , Kojda G. , Harrison DG Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. J Clin Invest2000; 105 (11):1631-9.

Drummond GR , Cai H. , Davis ME , Ramasamy S. , Harrison DG Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide. Circ Res2000; 86 (3): 347-54.

Landmesser UIF , McCann L. , Fukai T. , Somers MJ , Harrison DG Uncoupling of endothelial nitric oxide synthase leads to increased vascular suproxide produciton in deoxycorticosterone acetate (DOCA)-salt induced hypertension. Circulation2000; 102 (18): (Abstract) II-61.

Dimmeler S. , Rippmann V. , Weiland U. , Haendeler J. , Zeiher AM Angiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide. Circ Res1997; 81 (6): 970-6.

Yang Y. , Loscalzo J. Regulation of tissue factor expression in human microvascular endothelial cells by nitric oxide. Circulation2000; 101 (18): 2144-8.

Muller DN , Mervaala EM , Dechend R. et al. Angiotensin II (AT(1)) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy.Am JPathol2000; 157 (1):111-22.

Ichiki T. , Usui M. , Kato M. et al. Downregulation of angiotensin II type 1 receptor gene transcription by nitric oxide. Hypertension1998; 31 (1 Pt 2): 342-8.

Usui M. , Egashira K. , Kitamoto S. et al. Pathogenic role of oxidative stress in vascular angiotensin-converting enzyme activation in long-term blockade of nitric oxide synthesis in rats . Hypertension1999; 34 (4 Pt 1): 546-51.

Britten MB , Zeiher AM , Schachinger V. Clinical importance of coronary endothelial vasodilator dysfunction and therapeutic options. J Intern Med1999 ; 245 (4): 315-27.

Libby P. , Aikawa M. , Kinlay S. , Selwyn A. , Ganz P. Lipid lowering improves endothelial functions. Int J Cardiol2000; 74 Suppl 1: S3-S10.

Drexler H. , Hornig B. Endothelial dysfunction in human disease.JMol Cell Cardiol1999; 31 (1):51-60.

Oskarsson HJ , Heistad DD Oxidative stress produced by angiotensin too. Implications for hypertension and vascular injury. Circulation1997; 95 (3): 557-9.

Schiffrin EL , Deng LY , Larochelle P. Progressive improvement in the structure of resistance arteries of hypertensive patients after 2 years of treatment with an angiotensin I converting enzyme inhibitor. Comparison with effects of a beta-blocker. Am JHypertens1995 ; 8 (3): 229-36.

Schiffrin EL , Deng LY Comparison of effects of angiotensin I converting enzyme inhibition and beta-blockade for 2 years on function of small arteries from hypertensive patients. Hypertension1995 ; 25 (4 Pt 2): 699-703.

Mancini GB , Henry GC , Macaya C. et al. Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease.The TREND (Trial on Reversing ENdothelial Dysfunction) Study. Circulation1996; 94 (3): 258-65.

Chobanian AV , Haudenschild CC , Nickerson C. , Drago R. Antiatherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit. Hypertension1990; 15 (3): 327-31.

Varin R. , Mulder P. , Tamion F. et al. Improvement of endothelial function by chronic angiotensin-converting enzyme inhibition in heart failure : role of nitric oxide, prostanoids, oxidant stress, and bradykinin. Circulation2000; 102 (3): 351-6.

Schiffrin EL , Hayoz D. Role of AT1 angiotensin receptors in vascular remodeling in hypertension. In: Epstein M and Brunner HR , ed. Angiotensin II Receptor Antagonists. Philadelphia: Hanley & Belfus, Inc. 2000: 279-94.

Nishikawa K. Angiotensin AT1 receptor antagonism and protection against cardiovascular end-organ damage. J Hum Hypertens1998; 12 (5): 301-9.

Schiffrin EL , Park JB , Intengan HD , Touyz RM Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan. Circulation2000; 101 (14): 1653-9.

Nozawa Y. , Matsuura N. , Miyake H. , Yamada S. , Kimura R. Effects of TH-142177 on angiotensin II-induced proliferation, migration and intracellular signaling in vascular smooth muscle cells and on neointimal thickening after balloon injury. Life Sci1999; 64 (22): 2061-70.

Prasad A. , Tupas-Habib T. , Schenke WH et al. Acute and chronic angiotensin-1 receptor antagonism reverses endothelial dysfunction in atherosclerosis. Circulation2000; 101 (20): 2349-54.

Laufs U. , La Fata V. , Plutzky J. , Liao JK Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors . Circulation1998; 97 (12): 1129-35.

Vogel RA Cholesterol lowering and endothelial function. Am J Med1999; 107 (5):479-87.

Tsao PS , Cooke JP Endothelial alterations in hypercholesterolemia: more than simply vasodilator dysfunction. J Cardiovasc Pharmacol1998; 32 (Suppl 3): S48-53.

John S. , Schmieder RE Impaired endothelial function in arterial hypertension and hypercholesterolemia: potential mechanisms and differences.JHypertens2000; 18 (4): 363-74.

Sen CK , Packer L. Antioxidant and redox regulation of gene transcription. FASEB J1996;10 (7): 709-20.

Levine GN , Frei B. , Koulouris SN , Gerhard MD , Keaney JF Jr. , Vita JA Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation1996; 93 (6): 1107-13.

Ting HH , Timimi FK , Boles KS , Creager SJ , Ganz P. , Creager MA. Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus. J Clin Invest1996; 97 (1):22-8.

May JM How does ascorbic acid prevent endothelial dysfunction?Free Radic Biol Med2000; 28 (9): 1421-9.

Pearce KA , Boosalis MG , Yeager B. Update on vitamin supplements for the prevention of coronary disease and stroke . Am Fam Physician2000; 62 (6): 1359-66.

Rumiantseva OI , Tutel'ian VA , Pogozheva AV , Askol'zina SE , Lysenkova SL Biologically active food supplements in comprehensive therapy of patients with ischemic heart disease and hypertension and the background of overweight. Vopr Pitan2000; 69 (1-2): 44-6.

Barbacanne MA , Rami J. , Michel JB et al. Estradiol increases rat aorta endothelium-derived relaxing factor (EDRF) activity without changes in endothelial NO synthase gene expression: possible role of decreased endothelium-derived superoxide anion production. Cardiovasc Res1999; 41 (3): 672-81.

Nascimento CA , Kauser K. , Rubanyi GM Effect of 17beta-estradiol in hypercholesterolemic rabbits with severe endothelial dysfunction. Am J Physiol1999; 276 (5 Pt 2): H1788-94.