Koller B., Smithies O.Altering genes in animals by gene targeting. Annu Rev Immunol1992;10:705-30.
2.
Peach M.Renin-angiotensin system: biochemistry and mechanisms of action. Physiol Rev1977;57:313-70.
3.
Timmermans P. ,Wong P.,Chiu A. et al. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev1993 ;45:205-51.
4.
Murphy T., Alexander R., Griendling K., Runge M., Bernstein K.Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor. Nature1991;351:233-6.
5.
Sasaki K.,Yamano Y., Bardhan S. et al. Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor. Nature1991;351:230-2.
6.
Sandberg K., Ji H., Clark A., Shapira H., Catt K.Cloning and expression of a novel angiotensin II receptor subtype. J Biol Chem1992;267:9455-8.
7.
Sasamura H., Hein L., Krieger J., Pratt R., Kobilka B., Dzau V.Cloning, characterization, and expression of two angiotensin receptor (AT-1) isoforms from the mouse genome. Biochem Biophys Res Comm1992;185:253-9.
8.
Konishi H., Kuroda S., Inada Y., Fujisawa Y.Novel subtype of human angiotensin II type 1 receptor: cDNA cloning and expression . Biochem Biophys Res Comm1994;199:467-74.
9.
MacTaggartT. , Ito M., Smithies O., John S.Mouse angiotensin receptor genes agtr1b and agt-/- map to chromosomes 13 and 3. Mammalian Genome1997;8(4)(April):294-5.
10.
Burson J., Aguilera G., Gross K., Sigmund C.Differential expression of angiotensin receptor 1A and 1B in mouse. Am J Physiol1994;267:E260-7.
11.
Gasc J.-M, Shanmugam S., Sibony M., Corval P.Tissue-specific expression of type I angiotensin II subtypes: an in situ hybridisation study.Hypertension1994;24:531-7.
12.
Iwai N., Inagami T., Ohmichi N., Nakamura Y., Saeki Y., Kinoshita M.Differential regulation of rat AT1a and AT1b receptor mRNA. Biochem Biophys Res Comm1992;188:298-303.
13.
Carey R.,Wang Z., Siragy H.Role of the angiotensin type 2 receptor in the regulation of blood pressure and renal function. Hypertension2000;35:155-63.
14.
Nakajima M. , Hutchinson H., Fujinaga M. et al. The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer. Proc Natl Acad Sci USA1995;92:10663-7.
15.
Oliverio M. , Kim H., Ito M. et al. Reduced growth, abnormal kidney structure, and AT2 mediated BP regulation in mice lacking both AT2A and AT2B receptors for angiotensin II. Proc Natl Acad Sci USA1998;95:15496-501.
16.
Gomez R., Lynch K., Chevalier R. et al. Renin and angiotensinogen gene expression in maturing rat kidney . Am J Physiol1988;254:F582-7.
17.
Kakuchi J., Ichiki T., Kiyama S. et al. Developmental expression of renal angiotensin II receptor genes in the mouse. Kidney Int1995;47(1):140-7.
18.
Friberg P.,Sundelin B., Bohman S-O. et al. Renin-angiotensin system in neonatal rats: Induction of a renal abnormality in response to ACE-I or angiotensin II antagonism. Kidney Int1994;45:485-92.
19.
Tufro-McReddie A., Johns D., Geary K. et al. Angiotensin II type 1 receptor: role in renal growth and gene expression during normal development. AmJPhysiol1994;266:F911-8.
20.
Tufro-McReddie A.,Romano L., Harris J., Ferder L., Gomez R.Angiotensin II regulates nephrogenesis and renal vascular development. Am J Physiol1995 ; 269: F110-5.
21.
Kim H., Krege J., Kluckman K. et al. Genetic control of BP and the angiotensinogen locus. Proc Natl Acad Sci USA1995;92:2735-9.
22.
Niimura F., Labosky P.,Kakuchi J. et al. Gene targeting in mice reveals a requirement for angiotensin in the development and maintenance of kidney morphology and growth factor regulation. J Clin Invest1995;66:2947-54.
23.
Yababa M., Umemura S., Kihara M. et al. Altered development of vasculature in the kidney but not in other main organs in angiotensinogen-deficient mice. Hypertension1996;28:543A.
24.
Ito M., Oliverio M., Mannon P. et al. Regulation of BP by the type IA receptor for angiotensin II . Proc Natl Acad Sci USA1995;92:3521-5.
25.
Matsusaka T. , Nishimura H., Utsunomiya H. et al. Chimeric Mice Carrying 'Regional' Targeted Deletion of the Angiotensin Type 1A Receptor Gene: Evidence against the Role for Local Angiotensin in the In Vivo Feedback Regulation of Renin Synthesis in Juxtaglomerular Cells. J Clin Invest1996 ;98:1867-77.
26.
Sugaya T., Nishimatsu S., Tanimoto K. et al. Angiotensin II type 1a receptor-deficient mice with hypotension and hyperreninemia. J Biol Chem1995;270:18719-22.
27.
Oliverio M. , Madsen K., Best C. et al. Renal growth and development in mice lacking AT1A receptors for angiotensin II. Am J Physiol1998; 274:F43-50.
28.
Hein L., Barsh G., Pratt R., Dzau V., Kobilka B.Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice.Nature1995;377:744-7.
29.
Ichiki T., Labosky P., Shiota C. et al. Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor.Nature1995;377:748-50.
30.
Chen X., Li W., Yoshida H. et al. Targeting deletion of angiotensin type 1B receptor gene in the mouse.AmJPhysiol1997;272:F299-304.
31.
Tsuchida S. , Matsusaka T., Chen X. et al. Murine double nullizygotes of the angiotensin type 1A and 1B receptors duplicate severe abnormal phenotypes of angiotensinogen nullizygotes. J Clin Invest1998;101:755-60.
32.
Baker K., Booz G., Dostal D.Cardiac actions of angiotensin II: Role of an intra-cardiac renin-angiotensin system. Ann Rev Physiol1992;54:227.
33.
Powell J., Clozel J., Muller R. et al. Inhibitors of angiotensin converting enzyme prevent myointimal proliferation after vascular injury. Science1989;245:186-9.
34.
Esther C., Howard T., Marino E., Goddard J., Capecchi M., Bernstein K.Mice lacking angiotensin converting enzyme have low blood pressure, renal pathology, and reduced male fertility. Lab Invest1996;74:953-65.
35.
Miyazaki Y., Tsuchida S., Nishimura H. et al. Angiotensin induces the urinary peristaltic machinery during the perinatal period. J Clin Invest1998;102:1489-97.
36.
Bankir L., DeRouffignac D.Urinary concentrating ability: Insights from comparative anatomy. Am J Physiol1985;249:F643-666.
37.
Oliverio M., Dalnomdedieu M., Best C. et al. Abnormal water metabolism in mice lacking the type 1A receptor for angiotensin II. Am J Physiol2000; 278:F75-82.
BonnardeauxA,Davies E., Jeunemaitre X. et al. Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension.Hypertension1994;24:63-9.
40.
Benetos A., Gautier S., Ricard S. et al. Angiotensin-converting enzyme inhibitors: Influence of angiotensin-converting enzyme and angiotensin II type 1 receptor gene polymorphisms on aortic stiffness in normotensive and hypertensive patients. Circulation1996;94:698-703.
41.
Oliverio M. , Best C., Kim H., Arendshorst W., Smithies O., Coffman T.Angiotensin II responses in AT1A receptor-deficient mice: A Role for AT2B Receptors in BP Regulation.AmJPhysiol1997;272:F515-F520.
42.
Llorens-Cortes C., Greenberg B., Huang H., Corvol P.Tissular expression and regulation of type 1 angiotensin II receptor subtypes by quantitative reverse transcriptase-polymerase chain reaction analysis.Hypertension1994;24:538-548.
43.
Ruan X., Oliverio MO, Coffman TM, Arendshorst WJRenal vascular reactivity in mice: Ang II-induced renal vasoconstriction in mice lacking AT1A receptors. J Am Soc Nephrol1999; 10:2620-30.
44.
Johren O., Inagami T., Saavedra J.AT1A, AT1B, and AT12 angiotensinn receptor subtype expression in rat brain . Neuro Rep1995;6:2549-52.
45.
Kakar S., Riel K., Neill J.Differential expression of angiotensin II receptor subtype mRNAs (AT-1A and AT-1B) in the brain. Biochem Biophys Res Comm1992;185:688-92.
46.
Lenkei Z., Corvol P., Llorens-Cortes C.The angiotensin receptor subtype AT1A predominates in rat forebrain areas involved in blood pressure, body fluid homeostasis, and neuroendocrine control . Mol Brain Res1995;1:53-60.
47.
Davisson R. , Oliverio M., Coffman T., Sigmund C.Divergent functions of angiotensin II receptor isoforms in the brain. J Clin Invest2000;106:103-6.
48.
Ichikawa I. , Brenner B.Importance of efferent arteriolar vascular tone in regulation of proximal tubule fluid reabsorption and glomerulotubular balance in the rat. J Clin Invest1980;65:1192-201.
49.
Cogan M.Angiotensin II: a powerful controller of sodium transport in the early proximal tubule. Hypertension1990;15:451-8.
50.
Schuster V. , Kokko J., Jacobson H.Angiotensin II directly stimulates sodium transport in rabbit proximal convoluted tubules.J Clin Invest1984;73:507-15.
51.
Kojima I., Kojima K., Kruetter K., Rasmussen H.The temporal integration of the aldosterone secretory response occurs via two intracellular pathways. J Biol Chem1984 ;259:14448.
52.
Oliverio M. , Best C., Smithies O., Coffman T.Regulation of sodium balance and BP by theAT1A receptor for angiotensin II. Hypertension2000;35:550-4.
53.
Okubo S., Niimura F., Nishimura H. et al. Angiotensin-independent mechanism for aldosterone synthesis during chronic extracellular fluid volume depletion. J Clin Invest1997;99:855-60.