The influence of articular cartilage,subchondral and cancellous bone on the mechanical characteristics of the tibial plateau osteochondral unit

Abstract

This study investigates the relationship between the thickness of articular cartilage, subchondral, and cancellous bone with the biomechanical behaviour of the osteochondral unit, aiming to identify the dominant roles of these structures. The findings could assist in designing structures with compatible morphology, materials, and cartilage repair procedures for surgeons. Using bovine hindlegs, measurements of articular cartilage thickness were taken, and indentation and three-point bending tests were performed. The study found that the cartilage thickness was greater in the medial tibial plateau, particularly in the middle region, while the lateral plateau exhibited lower thickness but higher instantaneous modulus and stiffness, especially in the anterior region. Strong correlations were observed between osteochondral bone properties and the thickness of subchondral and cancellous bone in the medial tibial plateau. The biomechanical behaviour of the osteochondral unit showed regional variation, with bone thickness influencing the medial plateau cartilage thickness impacting the lateral plateau. This study provides a possible reference for surgeons to design effective strategies for treating cartilage damage.