Is there a role for progesterone in the treatment of severe head injury?

Abstract

Get full access to this article

View all access options for this article.

References

Ma J, Huang S, Qin S and You C. Progesterone for acute traumatic brain injury. Cochrane Database of Systematic Reviews 2012, Issue 10. Art. No.: CD008409.

Shakeri

Boustani

Pak

. Effect of progesterone administration on prognosis of patients with diffuse axonal injury due to severe head trauma. Clin Neurol Neurosurg 2013; 115: 2019–2022.

Skolnick

Maas

Narayan

. SYNAPSE trial investigators. a clinical trial of progesterone for severe traumatic brain injury. N Engl J Med 2014; 25(371): 2467–2676.

Wright

Yeatts

Silbergleit

. Very early administration of progesterone for acute traumatic brain injury. N Engl J Med 2014; 371: 2457–2466.