Preoperative Staging of Colorectal Cancer — Computed Tomography and Magnetic Resonance Imaging

Abstract

Cross-sectional imaging techniques are increasingly being used in the preoperative evaluation of patients with colorectal cancer. Both computed tomography (CT) and magnetic resonance (MR) imaging have been improved with significant advances of the technological hard- and software. This has contributed to high patient acceptance due to shorter examination times and more open configuration of the systems, consistent high quality images with better delineation of the normal abdomino-pelvic anatomy and pathology. New techniques such as CT-colonography have emerged from a research application to a clinical tool which can be used in different clinical settings. Phased-array receiver coils have significantly increased the usefulness of MR in the evaluation of rectal neoplasms due to the high resolution that can be obtained. New organ specific contrast agents for magnetic resonance imaging have facilitated the preoperative evaluation of liver metastases in favour of more invasive techniques with similar sensitivities. However, preoperative staging criteria for colorectal cancer using computed tomography and magnetic resonance imaging has to be updated and the results of new techniques have to be confirmed in large trials. In the future, further development of CT and MR may offer ‘one-stop-shopping’ protocols for both diagnosis, local and distant staging of colorectal cancer. Diffusion weighted MR-imaging, in vivo spectroscopy as well as further targeted imaging, such as with lymph node specific agents for MR may also prove to be helpful in the preoperative evaluation of patients with colorectal cancer.