This article examines the relationships between the indoor environment and the development of bronchial hyperreactivity and asthma. A large number of pollutants, both chemicals and biological agents, are detectable indoors, including several allergens, i.e. substances that can stimulate an IgE response. The sources most widely recognised as indoor allergens for asthma and rhinitis are mites and pets. A relationship between levels of exposure to these agents and the development of sensitisation or asthma in genetically susceptible indi viduals has been clearly demonstrated together with a reduction of symptoms after the application of avoidance procedures. Apart from preventative proce dures directed to the patient, which are expensive and time-consuming, great benefit could also come, in the future, from addressing the problems of inade quacy in buildings, for instance by improving ventilation rates and heating systems.
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