Day-averaged outdoor aerosol concentrations from fixed ambient air monitoring stations are associated with the daily lung dose of an individual and the consequent health effects in most studies. The applicability of such measurements for dose assessment is evaluated in this study by comparing the estimated total and regional lung doses using the above concentrations, continuous (hourly) or day-averaged, to the dose derived from actual exposure. Dosimetric calculations are performed using experimentally determined indoor and outdoor concentrations during realistic exposure under variant physical exertion in both environments. The results show that the daily dose can be closely estimated by day-averaged data.
Wichmann HE, Peters A.: Epidemiological evidence of ultrafine particle exposure: Philos Transact A Math Phys Eng Sci2000;358: 2751-2768.
2.
Lippmann M., Ito K.: Contributions that epidemiological studies can make to the search for a mechanistic basis for the health effects of ultrafine and larger particles: Philos Transact A Math Phys Eng Sci2000; 1775:2787-2797.
3.
Pope CA, Burnett RT, Thun MJ, Calle EE, Krewski D., Ito K., Thurston GD: Lung Cancer, Cardio-pulmonary mortality and Long-term exposure to fine particulate air pollution: J Am Med Assoc2002;287: 1132-1141.
4.
Neuberger M., Schimekc MG, Horak F.Jr, Moshammerb H., Kundib M., Frischerd T., Gomisceka B., Puxbauma H., Hauck H., AUPHEP-Team: Acute effects of particulate matter on respiratory diseases, symptoms and functions: epidemiological results of the Austrian Project on Health Effects of Particulate Matter (AUPHEP): Atmos Environ2004;38:3971-3981.
5.
Dominici F., McDermott A., Daniels M., Zeger SL, Samet JM: Revised analyses of the national morbidity, mortality, and air pollution study: mortality among residents of 90 cities: J Toxicol Environ Health A Current Issues2005;68:1071-1092.
6.
Analitis A., Katsouyanni K., Dimakopoulou K., Samoli E., Nokolopoulos AK, Perasakis Y., Touloumi G., Schwartz J., Anderson HR, Cambra K., Forastiere F., Zmirou D., Vonk JM, Clancy L., Kriz B., Bobvos J., Pekkanen J.: Short-term effects of ambient particles on cardiovascular and respiratory mortality: Epidemiol2006;17:230-233.
7.
Ozkaynak H., Spengler J.; in Wilson R, Spengler J (eds): The role of outdoor particulate matter in assessing total human exposure in particles in our air: concentrations and health effects , chap 4 Cambridge, MA, Harvard University Press, 1996.
8.
US Environmental Protection Agency: Air quality criteria for particulate matter, EPA-600/P-99/002aF, NC, Research Triangle Park, 2004.
9.
Wallace L.: Indoor Particles: A Review: J Air Waste Manag Assoc1996;46:98-126.
10.
Wallace L.: Correlations of personal exposure to particles with outdoor air measurements: A review of recent studies: Aerosol Sci Technol2000;32:15-25.
11.
He C., Morawska L., Hitchins J., Gilbert D.: Contribution from indoor sources to particle number and mass concentrations in residential houses: Atmos Environ2004;38:3405-3415.
12.
Mitsakou C., Housiadas C., Eleftheriadis K., Vratolis S., Helmis C., Asimakopoulos D.: Lung deposition of fine and ultrafine particles outdoors and indoors during a cooking event and a no activity period: Indoor Air2007; 17:143- 152.
13.
Lazaridis M., Dahlin E., Hansen JE, Smolik J., Schmidbauer N., Moravec P., Zdimal V., Hermansen O., Glytsos T., Svendby T., Dye C.: Indoor/Outdoor particulate matter measurements in two residential houses in Oslo, Norway: J Aerosol Sci2003;34:S1367-S1368.
14.
Lazaridis M. , Aleksandropoulou V., Smolik J., Hansen JE, Glytsos T., Kalogerakis N., Dahlin E.: Physico-chemical characterization of indoor/outdoor particulate matter in two residential houses in Oslo, Norway: measurements overview and physical properties - URBAN-AEROSOL Project: Indoor Air2006;16:282-295.
15.
Berner A., Lürzer C.: Mass size distributions of traffic aerosols atVienna: J Phys Chem1980; 84:2079-2083.
16.
Norwegian Institute for Air Research (NILU) : The NILU tracer gas technique, Factsheet 8-1995 E (http://www.nilu.no), Kjeller, 1995.
17.
O'Shaughnessy PT, Raabe OG: A comparison of cascade impactor data reduction methods: Aerosol Sci Technol2003;37:187-200.
18.
Hinds WC: Aerosol technology: properties, behavior, and measurement of airborne particles . New York, John Wiley & Sons, Inc. 1999.
19.
Morawska L., Congrong H.; in Morawska L, Salthammer T (eds): Indoor environment: airborne particles and settled dust; Weinheim, Willey -VCHVerlagGmbH&Co.KGaA, 2004, pp. 190-224.
20.
International Commission on Radiological Protection publication Human Respiratory tract Model for Radiological Protection ICRP Publication 66, Oxford, Pergamon Press, 1994.
21.
Eurostat: How Europeans spend their time, everyday life of women and men, data 1998-2002, Luxembourg, Office for Official Publications of the European Communities, 2004.
22.
Central Bureau of Statistics, Norway: The time budget surveys, survey of level of living, time budget, Oslo, Time Use Survey2000, 2002.
23.
Clench-Aas J., Bartonova A., Gronskei KE, Hagen LO, Braathen OA, Walker SE: Air pollution exposure monitoring and estimation. Part VI. Ambient exposure of adults in an industrialised region: J Environ Monit1999;1: 341-347.
24.
Sioutas C., Kim S., Chang M., Terrell LL, Gong Jr H.: Field evaluation of a modified DataRAM MIE scattering monitor for real-time PM2.5 mass concentration measurements: Atmos Environ2000;34:4829-4838.
25.
Zhang Q., Canagaratna MR, Jayne JT, Worsnop DR, Jimenez JL: Time and size-resolved chemical composition of submicron particles in Pittsburg-Implications for aerosol sources and processes: J Geophys Res Atmos2005;110:D07S09.
26.
Brown JS: Particle inhalability at low wind speeds: Inhal Toxicol2005;14:831-837.
27.
Menache MG, Miller FJ, Raabe OG: Particle inhalability curves for humans and small laboratory animals: Ann Occup Hyg1995;39: 317-328.
28.
McMurry PH: A review of atmospheric aerosol measurements: Atmos Environ2000; 34:1959-1999.
29.
Smolík J., Lazaridis M., Moravec P., Schwarz J., Zaripov SK, Ždímal V.: Indoor Aerosol Particle Deposition in an Empty Office: Water Air Soil Pollut2005;165:301-312.
30.
Long CM, Suh HH, Catalano PJ, Koutrakis P.: Using time and size-resolved particulate data to quantify indoor penetration and deposition behavior: Environ Sci Technol2001;35:2089-2099.
31.
Franck U., Herbath O., Wehner B., Wiedendohler A., Manjarrez M.: How do the indoor size distributions of airborne submicron and ultrafine particles in the absence of significant indoor sources depend on outdoor distributions ?: Indoor Air2003; 13:174-181.
32.
Salma I., Balashazy I., Hofmann W., Zaray G.: Effect of physical exertion on the deposition of urban aerosols in the human respiratory tract: Aerosol Sci2002;33:983-997.
33.
Salma I., Balashazy I., Winkler-Heil R., Hofmann W., Zaray G.: Effect of particle mass size distribution on the deposition of aerosols in the human respiratory system: Aerosol Sci2002;33:119-132.
34.
Venkataraman C., Kao AS: Comparison of particle lung doses from the fine and coarse fractions of urban PM10 aerosols: Inhal Toxicol1999;11:151-169.
