Abstract
Among the subjects classified as possibly or definitely demented 60% had suspected or definitely cerebral atrophy on CTs. Among the subjects classified as definitely demented 42% had definite cerebral atrophy. None of the referents had definite atrophy on CT. Regional cerebral blood flow was significantly decreased among subjects with cerebral atrophy. Some group overlap was evident as 12 subjects classified as definitely demented had normal CTs. This overlap showed that the absence of cerebral atrophy did not exclude the presence of dementia. On the other side, cerebral atrophy should not be found by a mere coincidence among persons under the age of sixty but indicates the presence of dementia.
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