In a five-year follow-up of a random sample of men aged 55 the association between risk factors and premature death was analysed. The overall mortality in five years was 5.8%. The mortality among the smokers was 8%; among non-smokers 2%. Of 16 cancer deaths all were smokers except one who was an ex-smoker. In spite of treatment of hypertension (>165/110 mmHg) there was an association between high blood pressure and premature death, particularly when cause of death was cardiovascular disease. There was no association between premature death and serum cholesterol, serum triglycerides or physical activity. The study is based on 703 men, of whom 41 died. The autopsy frequency was 93%. Only 3 men (0.4%) were lost to follow-up.
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References
1.
1. Carlsson, L. A. & Böttiger, L. E.: Ischaemic heart-disease in relation to fasting values of plasma triglycerides and cholesterol. Stockholm prospective study. Lanceti:865, 1972.
2.
2. Cederlöf, R., Friberg, L., Hrubec, Z. & Lorich, U.: The relationship of smoking and some social covariables to mortality and cancer morbidity. The Karolinska Institute, Stockholm, 1975.
3.
3. Doll, R. & Hill, A. B.: Mortality in relation to smoking: Ten years' observations of British doctors. Br Med Ji: 1399 & i: 1460, 1964.
4.
4. Dyer, A. R., Stamler, J., Berkson, D. M., Lindberg, H. A. & Stevens, E.: High blood-pressure: A risk factor for cancer mortality?Lanceti: 1051, 1975.
5.
5. Freis, E. D.: Effects of treatment on morbidity in hypertension. II. Results in patients with diastolic blood pressure averaging 90 through 114 mmHg. JAMA213:1143, 1970.
6.
6. Furberg, C. & Isacsson, S. O.: Rökstopp ger förlängt liv. Läkartidningen72:2936, 1975.
7.
7. Gordon, T. & Kannel, W. B.: Predisposition to atherosclerosis in the head, heart and legs. The Framingham Study, JAMA221:661, 1972.
8.
8. Hammond, E. C.: Smoking in relation to the death rates of one million men and women. Natl Cancer Inst Monogr19:127, 1966.
9.
9. Isacsson, S. O.: Venous occlusion plethysmography in 55-year-old men. A population study in Malmö, Sweden. Acta Med Scand, Suppl. 537, 1972.
10.
10. Isacsson, S. O. & Janzon, L.: Results of a quit-smoking research project in a randomly selected population. Scand J Soc Med4:25, 1976.
11.
11. Isacsson, S. O., Lindell, S. E., Carle, T. & Malmborg, R. O.: Detection, treatment and follow-up of hypertension in a community sample of 55-year-old men. Scand J Soc Med3:93, 1975.
12.
12. Janzon, L.: The effect of smoking and smoking cessation on peripheral circulation and fibrinolysis. A population study in 59-year-old men. Acta Chir Scand, Suppl. 451, 1974.
13.
13. Keys, A.: Coronary heart disease—the global picture. Atherosclerosis22:149, 1975.
14.
14. Keys, A., Aravanis, C., Blackburn, H., Buchem, F. S. P., van, Buzina, R., Djordjevic, B. S., Fidanza, F., Karvonen, M. J., Menotti, A., Puddu, V. & Taylor, H. L.: Probability of middle-aged men developing coronary heart disease in five years. Circulation45:815, 1972.
15.
15. Lannerstad, O., Sternby, N. H., Isacsson, S. O., Lindgren, G. & Lindell, S. E.: Effects of a population study on mortality and causes of death in middle-aged men. A prospective study from 1970 to 1974 of men in Malmö, born 1914. Accepted for publication in Scand J Soc Med.
16.
16. Rogot, R.: Smoking and general mortality among US veterans 1954-1969. DHEW Publication No. (NIH)74:544, 1974.
17.
17. Smoking or Health: A report of The Royal College of Physicians. Pitman Medical Publishing Co. Ltd., 1977.
18.
18. Tibblin, G., Wilhelmsen, L. & Werkö, L.: Risk factors for myocardial infarction and death due to ischemic heart disease and other causes. Am J Cardiol35:514, 1975.
19.
19. Truett, J., Cornfield, J. & Kannel, W.: A multivariate analysis of the risk of coronary heart disease in Framingham. J Chronic Dis20:511, 1967.
20.
20. Werkä, L.: Risk factor and coronary heart disease—facts or fancy. Am Heart J91:87, 1976.
21.
21. Wilhelmsen, L.: The myocardial infarction clinic in Gäteborg—organization and preliminary results. Pehr Dubb J4:43, 1969.
22.
22. Wilhelmsen, L., Wedel, H. & Tibblin, G.: Multivariate analysis of risk factors for coronary heart disease. Circulation48:950, 1973.
