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Abstract

Background: Although, divorce is considered to have a negative impact on morbidity, very little is known concerning exposure to divorce and risk of infectious diseases. We aimed to investigate the association between divorce and subsequent hospital contacts with infectious diseases. Methods: We performed a nation-wide cohort study, including all Danish men and women (n≈5.6 million) alive on the 1 January 1982 or later, and followed them for infectious disease diagnosed in hospital settings from 1982 to 2010. The association between divorce and risk of infectious diseases was evaluated through rate ratios (RRs) comparing incidence rates of infectious diseases between divorced and married pesons. Results: Compared with married persons, divorced persons were overall at a 1.48 fold (RR=1.48 (95% CI: 1.47–1.50)) increased risk of hospital-diagnosed infectious diseases (RR adjusted for sex, age, period, income and education). The risk of infectious diseases was slightly more pronounced for divorced women (RR=1.54 (1.52–1.56)) than divorced men ((RR=1.42 (1.41–1.44)). The increased risk remained almost unchanged even more than 15 years after the divorce. Young age at divorce, short duration of marriage and number of divorces further increased the risk of infectious diseases, whereas number of children at time of divorce had no impact on risk of hospital-diagnosed infectious diseases following the divorce. Conclusions: Divorce appears to have a moderate but long lasting impact on the risk of infectious diseases. The underlying mechanism is unknown but shared risk factors predicting divorce and infectious diseases could contribute to our findings.

Keywords

Stressful life event divorce hospital-diagnosed infectious diseases nation-wide cohort study

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References

Lange

. Befolkningsudvikling siden 1960. www.dst.dk/upload/1995.pdf.

Verbrugge

. Marital status and health. J Marr Fam 1979;267–85.

Engstrom

Khan

Zia

. Marital dissolution is followed by an increased incidence of stroke. Cerebrovasc Dis 2004;18:318–24.

Sbarra

Nietert

. Divorce and death: forty years of the Charleston Heart Study. Psychol Sci 2009;20:107–13.

Shor

RN ugyi

Schwartz

. Meta-analysis of marital dissolution and mortality: reevaluating the intersection of gender and age. Soc Sci Med 2012;75:46–59.

Bruce

Kim

. Differences in the effects of divorce on major depression in men and women. Am J Psychiatry 1992;149:914–7.

Svedin

Wadsby

. The presence of psychiatric consultations in relation to divorce. Acta Psychiatr Scand 1998;98:414–22.

Yip

Thorburn

. Marital status and the risk of suicide: experience from England and Wales, 1982–1996. Psychol Rep 2004;94:401–7.

Eng

Kawachi

Fitzmaurice

. Effects of marital transitions on changes in dietary and other health behaviours in US male health professionals. J Epidemiol Community Health 2005;59:56–62.

10.

Lee

Cho

Grodstein

. Effects of marital transitions on changes in dietary and other health behaviours in US women. Int J Epidemiol 2005;34:69–78.

11.

Kudielka

Kirschbaum

. Sex differences in HPA axis responses to stress: a review. Biol Psychol 2005;69:113–32.

12.

Kiecolt-Glaser

Fisher

Ogrocki

. Marital quality, marital disruption, and immune function. Psychosom Med 1987;49:13–34.

13.

Pedersen

Gotzsche

Moller

. The Danish Civil Registration System. A cohort of eight million persons. Dan Med Bull 2006;53:441–9.

14.

Andersen

Madsen

Jorgensen

. The Danish National Hospital Register. A valuable source of data for modern health sciences. Dan Med Bull 1999;46:263–8.

15.

Harell

FE . General aspects of fitting regression models. Regression modeling strategies: with applications to linear models, logistic regression and survival analysis. New York: Springer; 2001. pp. 20–3.

16.

Simonsen

Frisch

Ethelberg

. Socioeconomic risk factors for bacterial gastrointestinal infections. Epidemiology 2008;19:282–90.

17.

Cohen

Tyrrell

Smith

. Psychological stress and susceptibility to the common cold. N Engl J Med 1991;325:606–12.

18.

Miller

Cohen

Pressman

. Psychological stress and antibody response to influenza vaccination: when is the critical period for stress, and how does it get inside the body? Psychosom Med 2004;66:215–23.

19.

Glaser

Pearson

Bonneau

. Stress and the memory T-cell response to the Epstein-Barr virus in healthy medical students. Health Psychol 1993;12:435–42.

20.

Dupre

Beck

Meadows

. Marital trajectories and mortality among US adults. Am J Epidemiol 2009;170:546–55.

21.

Cheung

Sloggett

. Health and adverse selection into marriage: evidence from a study of the 1958 British birth cohort. Public Health 1998;112:309–11.

22.

Amato

Previti

. People’s reasons for divorcing: Gender, social class, the life course, and adjustment. J Family Issues 2003;24:602–626.

23.

Rogge

Bradbury

Hahlweg

. Predicting marital distress and dissolution: refining the two-factor hypothesis. J Fam Psychol 2006;20:156–9.

24.

Lahey

. Public health significance of neuroticism. Am Psychol 2009;64:241–56.

25.

Lund

Holstein

Osler

. Marital history from age 15 to 40 years and subsequent 10-year mortality: a longitudinal study of Danish males born in 1953. Int J Epidemiol 2004;33:389–97.

26.

Schone

Weinick

. Health-related behaviors and the benefits of marriage for elderly persons. Gerontologist 1998;38:618–27.

27.

Schor

. Family pediatrics: report of the Task Force on the Family. Pediatrics 2003;111[Pt 2]:1541–71.

28.

Verbrugge

Wingard

. Sex differentials in health and mortality. Health Matrix 1987;5:3–19.

29.

Corney

. Sex differences in general practice attendance and help seeking for minor illness. J Psychosom Res 1990;34:525–34.

30.

Benfield

Jensen

Nordestgaard

. Influence of diabetes and hyperglycaemia on infectious disease hospitalisation and outcome. Diabetologia 2007;50: 549–54.

Divorce and risk of hospital-diagnosed infectious diseases

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