Alzheimer's disease (AD) is a common neurodegenerative disorder with a complex pathogenesis. Oxidative stress, neuroinflammation and apoptosis play key roles in the occurrence and development of AD. The Nrf2/HO-1 signaling pathway, as an important endogenous antioxidant stress pathway in cells, is of great significance in combating oxidative damage and neurodegeneration. In recent years, an increasing number of studies have shown that traditional Chinese medicine can exert therapeutic effects on AD by regulating the Nrf2/HO-1 signaling pathway. This article aims to review the research progress of traditional Chinese medicine in regulating the Nrf2/HO-1 signaling pathway for the treatment of AD, providing new ideas and strategies for the treatment of AD.
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