The Demise of Scientific Medicine? Responding to the Challenge of Populist Medicine and Institutional Mistrust

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Aggarwal

N. K.

(2025). Centering disadvantaged, minoritized families in autism education evaluations. Anthropology & Education, 56(3), 370026. https://doi.org/10.1111/aeq.70026

American College of Medical Toxicology (2026). ACMT Position Statement: ACMT responds to the acetaminophen and autism controversy. Journal of Medical Toxicology, 22(1), 106–109. https://doi.org.https://doi.org/10.1007/s13181-025-01116-2.

American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders: Third edition. American Psychiatric Association.

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders: Fifth edition. American Psychiatric Association.

Bazzano

Zeldin

Schuster

Barrett

Lehrer

(2012). Vaccine-related beliefs and practices of parents of children with autism spectrum disorders. American Journal on Intellectual and Developmental Disabilities, 117(3), 233–242. https://doi.org.10.1352/1944-7558-117.3.233

Bérard

Cottin

Leal

L. F.

Picot

Pleau

Damkier

Cucherat

Alwan

Winn

L. M.

Carleton

B. C.

Bertoldi

A. D.

Grandi

S. M.

Masarwa

Dodin

Ceulemans

Platt

R. W.

Nourredine

Gram

E. B.

Veroniki

A. A.

Massardier

Tricco

A. C.

(2025). Systematic review and meta-analysis: Acetaminophen use during pregnancy and the risk of neurodevelopmental disorders in childhood. Journal of the American Academy of Child and Adolescent Psychiatry, 65(4), 484–504. https://doi.org.10.1016/j.jaac.2025.09.031.

Bhui

O’Brien

Upthegrove

Tsai

A. C.

Soomro

Newton-Howes

Broome

M. R.

Forrester

Casey

Doherty

A. M.

Lee

Kaufman

K. R.

(2025). Protecting and promoting editorial independence. The British Journal of Psychiatry, 226(1), 4–6. https://doi.org/10.1192/bjp.2024.6.

C-Span. (2025). Health and Human Services Secretary Kennedy testifies on health care agenda, part 1. September 4. https://www.c-span.org/program/senate-committee/health-and-human-services-secretary-kennedy-testifies-on-health-care-agenda-part-1/664946

Camargo

K. R.

(2025). Trump 2 at war with science. Cadernos de Saúde Pública, 41(44), e00027025. https://doi.org.10.1590/0102-311XEN027025

10.

Centers for Disease Control. (2025). Autism and vaccines. November 19. https://www.cdc.gov/vaccine-safety/about/autism.html

11.

Collins

Evans

(2017). Why democracies need science. John Wiley & Sons.

12.

Collins

Evans

Durant

Weinel

(2023). The third wave and populism: Scientific expertise as a check and balance. In Eyal

Medvetz

(Eds.), The Oxford handbook of expertise and democratic politics (pp. 52–75). Oxford University Press.

13.

Conway-Moore

McKinlay

A. R.

Birch

J. M.

Graham

Oliver

E. J.

Bambra

Kelly

M. P.

Bonell

(2025). How populist-aligned views are reflected in people's accounts of the receipt of public health interventions: A systematic review of qualitative studies. Social Science & Medicine, 381, 118312. https://doi.org/10.1016/j.socscimed.2025.118312.

14.

Decoteau

C. L.

Sweet

P. L.

(2024). Vaccine hesitancy and the accumulation of distrust. Social Problems, 71(4), 1231–1246. https://doi.org/10.1093/socpro/spad006

15.

Dyer

(2025a). Relief agencies in shock as Trump cuts 90% of USAID funding. British Medical Journal, 388, r445. https://doi.org.10.1136/bmj.r445

16.

Dyer

(2025b). Trump halts new research grants to foreign scientists. British Medical Journal, 389, r906. https://doi.org.10.1136/bmj.r906

17.

Dyer

(2025c). RFK Jr threatens to stop US scientists from publishing in major medical journals. B.M.J., 389, r1110. https://doi.org.10.1136/bmj.r1110

18.

Fieldhouse

(2025). RFK Jr demanded a vaccine study be retracted – The journal said no. Nature, 645(8079), 13–14. https://doi.org.10.1038/d41586-025-02682-9

19.

Foucault

(1995). Discipline and punish: The birth of the prison (A. Sheridan, Trans.). Vintage Books.

20.

Gostin

L. O.

(2025). The Trump presidency: Cascading global shocks on global health. PLOS Global Public Health, 5(11), e0005385. https://doi.org.10.1371/journal.pgph.0005385

21.

Grant Witness. (2026). Grant witness. https://grant-witness.us/nih-data.html

22.

Heidt

Ledford

(2025). Vaccine sceptic RFK Jr is now a powerful force in US science: What will he do? Nature, in press. https://doi.org.10.1038/d41586-025-00439-y

23.

HHS Press Office. (2025). HHS takes bold step to restore public trust in vaccines by reconstituting ACIP. U.S. Department of Health & Human Services. June 9. https://www.hhs.gov/press-room/hhs-restore-public-trust-vaccines-acip.html

24.

Hoffman

(2026). H.H.S. reverses decision to cut $2 billion for mental health and addiction services. New York Times, January 14. https://www.nytimes.com/2026/01/14/health/samhsa-funding-cuts.html

25.

Jama

Ali

Lindstrand

Butler

Kulane

(2018). Perspectives on the measles, mumps and rubella vaccination among Somali mothers in Stockholm. International Journal of Environmental Research and Public Health, 15(11), 2428. https://doi.org.10.3390/ijerph15112428

26.

Jasanoff

(2004). The idiom of co-production. In Jasanoff

(Ed.), States of knowledge: The co-production of science and social order (pp. 1–12). Routledge.

27.

Kekatos

(2025). Federal judges weigh reviving court cases linking Tylenol to autism. ABC News, November 21. https://abcnews.go.com/Health/federal-judges-weigh-reviving-court-cases-linking-tylenol/story?id=127668037

28.

Kirmayer

L. J.

(2024a). The fragility of truth: Social epistemology in a time of polarization and pandemic. Transcultural Psychiatry, 61(5), 701–713. https://doi.org/10.1177/13634615241299556

29.

Kirmayer

L. J.

(2024b). Science and sanity: A social epistemology of misinformation, disinformation, and the limits of knowledge. Transcultural Psychiatry, 61(5), 795–808. https://doi.org/10.1177/13634615241296301

30.

Kirmayer

L. J.

Bennegadi

Kastrup

M. C.

(2017). Cultural awareness and responsiveness in person-centered psychiatry. In Mezzich

J. E.

Botbol

Christodoulou

G. N.

Cloninger

C. R.

Salloum

I. M.

(Eds.), Person centered psychiatry (pp. 77–95). Springer Nature.

31.

Kirmayer

L. J.

Crafa

(2014). What kind of science for psychiatry? Frontiers in Human Neuroscience, 8, 435. https://doi.org.10.3389/fnhum.2014.00435

32.

Kleinman

(1996). How is culture important for DSM-IV? In Mezzich

J. E.

Kleinman

Fabrega

Jr. Parron

D. L.

(Eds.), Culture and psychiatric diagnosis: A DSM-IV perspective (pp. 15–26). American Psychiatric Press, Inc.

33.

Larson

H. J.

(2020). Stuck: how vaccine rumors start – And why they don't go away. Oxford University Press.

34.

Looi

M.-K.

(2025). Trump watch: Leaked plan to slash NIH budget in half, CDC contradicts RFK Jr on autism, and more. B.M.J., 389, r798. https://doi.org.10.1136/bmj.r798

35.

Louwen

Deuster

MacAuliffe

F. M.

Jacobsson

Geary

Fleischman

Khara

A.-B.

(2025). Paracetamol (acetaminophen) use during pregnancy and autism risk: Evidence does not support causal association. International Journal of Gynecology & Obstetrics, 171(3), 915–919. https://doi.org/10.1002/ijgo.70577

36.

Malakoff

(2025). How Trump upended science. Science, 388(6747), 576–577. https://doi/org.10.1126/science.ady7724

37.

Mendenhall

(2024). Trust, individualism, and the logics of care in Middle America during the first year of the COVID-19 pandemic. Transcultural Psychiatry, 61(5), 724–733. https://doi.org/10.1177/13634615231213839

38.

Mervis

(2025a). Trump orders cause chaos at science agencies. Science, 387(6734), 564–565. https://doi.org.10.1126/science.adw4912

39.

Mervis

(2025b). Trump moves to politicize decisions on science grants. Science, 389(6761), 675. https://doi.org.10.1126/science.aeb4276

40.

Nature. (2025). Trump 2.0: An assault on science anywhere is an assault on science everywhere. Nature, 639(8053), 7–8. https://doi.org.10.1038/d41586-025-00562-w

41.

NIH. (2024). Rescinded – Final scientific integrity policy of the National Institutes of Health: NOT-OD-24-178. https://grants.nih.gov/grants/guide/notice-files/NOT-OD-24-178.html#:∼:text=Scientific%20integrity%20aims%20to%20make,Safeguard%20scientific%20integrity

42.

O’Dell

Rosqvist

H. B.

Ortega

Brownlow

Orsini

(2016). Critical autism studies: Exploring epistemic dialogues and intersections, challenging dominant understandings of autism. Disability & Society, 31(2), 166–179. https://doi.org/10.1080/09687599.2016.1164026

43.

Pigliucci

(2010). Nonsense on stilts: How to tell science from bunk. University of Chicago Press.

44.

Rathje

J. K.

Roozenbeek

Van Bavel

J. J.

Van Der Linden

(2022). Social media behavior is associated with vaccine hesitancy. PNAS Nexus, 1(4), pgac207. https://doi.org/10.1093/pnasnexus/pgac207

45.

Reich

J. A.

(2016). Calling the shots: Why parents reject vaccines. New York University Press.

46.

Reuters. (2025). WHO to lose nearly a quarter of its workforce – 2,000 jobs – due to US withdrawing funding. The Guardian, November 18. https://www.theguardian.com/world/2025/nov/19/world-health-organisation-to-cut-jobs-due-to-us-withdrawing-funding

47.

Richlin

J. B.

(2023). From iatrogenesis to vaccine skepticism: US mothers’ negative vaccine perceptions and non-vaccination practices as reverberations of medical harm. Medical Anthropology Quarterly, 37(2), 118–133. https://doi.org/10.1111/maq.12764

48.

Sanci

(2026). Canada’s reliance on U.S. health data under spotlight after federal health minister says she ‘cannot trust’ American vaccine policy. The Hill Times, January 12. https://www.hilltimes.com/story/2026/01/12/canadas-reliance-on-u-s-health-info-under-spotlight-after-health-ministers-comments-on-american-vaccine-policy/487256/

49.

Science News Staff. (2025). Trump proposes massive cuts to research spending. Science, 388(6747), 566–567. https://doi.org.10.1126/science.ady8072

50.

Sheikh

Allotey

Sobhy

Plana

M. N.

Martinez-Borros

Naidu

Junaid

Sofat

Mol

B. W.

Kenny

L. C.

Gladstone

Teede

Zamora

Thangaratinam

(2025). Maternal paracetamol (Acetaminophen) use during pregnancy and risk of autism spectrum disorder and attention deficit/hyperactivity disorder in offspring: umbrella review of systematic reviews. British Medical Journal, in press. https://doi.org.10.1136/bmj-2025-088141.

51.

Sobo

E. J.

(2015). Social cultivation of vaccine refusal and delay among Waldorf (Steiner) school parents. Medical Anthropology Quarterly, 29(3), 381–399. https://doi.org.10.1111/maq.12214

52.

Suelzer

E. M.

Deal

Hanus

K. L.

Ruggeri

Sieracki

Witkowski

(2019). Assessment of citations of the retracted article by Wakefield et al. With fraudulent claims of an association between vaccination and autism. JAMA Network Open, 2(11), e1915552. https://doi.org.10.1001/jamanetworkopen.2019.15552

53.

Taylor

(2025). RFK Jr dismisses entire CDC vaccine advisory panel. B.M.J., 389, r1206. https://doi.org.10.1136/bmj.r1206

54.

The Lancet. (2025). RFK Jr and MAHA: Dangerous, emboldened, and escalating. The Lancet, 406(10505), 779. https://doi.org.10.1016/S0140-6736(25)01683-6

55.

The Lancet Public Health. (2025). Public health under Trump 2.0: The first 50 days. The Lancet Public Health, 10(4), e264. https://doi.org.10.1016/S2468-2667(25)00071-4

56.

The White House. (2025). FACT: Evidence suggests link between acetaminophen, autism. September 22. https://www.whitehouse.gov/articles/2025/09/fact-evidence-suggests-link-between-acetaminophen-autism/

57.

Thompson

Kozlov

(2025). Trump team removes senior NIH chiefs in shock move. Nature, in press. https://doi.org.10.1038/d41586-025-01071-6

58.

Tollefson

Garisto

Ledford

(2025). Will US science survive Trump 2.0? Nature, 641(8061), 26–30. https://doi.org.10.1038/d41586-025-01295-6

59.

U.S. Food and Drug Administration. (2025). FDA responds to evidence of possible association between autism and acetaminophen use during pregnancy. September 22. https://www.fda.gov/news-events/press-announcements/fda-responds-evidence-possible-association-between-autism-and-acetaminophen-use-during-pregnancy

60.

Waltz

(2014). Worlds of autism: Across the spectrum of neurological difference. Disability & Society, 29(8), 1337–1338. https://doi.org.10.1080/09687599.2014.934064

61.

Weiss

M. G.

Somma

(2007). Explanatory models in psychiatry. In Bhugra

Bhui

(Eds.), Textbook of cultural psychiatry (pp. 127–140). Cambridge University Press.

62.

Wilson

S. L.

Wiysonge

(2020). Social media and vaccine hesitancy. BMJ Global Health, 5(10), e004206. https://doi.org/10.1136/bmjgh-2020-004206

63.

Zakirova-Engstrand

Hirvikoski

Allodi

M. W.

Roll-Pettersson

(2020). Culturally diverse families of young children with ASD in Sweden: Parental explanatory models. PLoS One, 15(7), e0236329. https://doi.org.10.1371/journal.pone.0236329